Literature DB >> 7958966

Structure of the murine interferon alpha/beta receptor-encoding gene: high-frequency rearrangements in the interferon-resistant L1210 cell line.

G Lutfalla1, G Uzé.   

Abstract

The structure of the murine IFNAR gene, encoding the interferon alpha/beta receptor, is reported. The gene has eleven exons dispersed in about 23 kb of genomic DNA. The nature of the rearrangements affecting this gene in interferon-resistant (IFNR) L1210 mutant cell lines is described.

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Year:  1994        PMID： 7958966     DOI： 10.1016/0378-1119(94)90710-2

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  2 in total

1.  A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses.

Authors:  S Y Hwang; P J Hertzog; K A Holland; S H Sumarsono; M J Tymms; J A Hamilton; G Whitty; I Bertoncello; I Kola
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

2.  Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo.

Authors:  Winfried Barchet; Marina Cella; Bernhard Odermatt; Carine Asselin-Paturel; Marco Colonna; Ulrich Kalinke
Journal:  J Exp Med       Date:  2002-02-18       Impact factor: 14.307
  2 in total

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