Literature DB >> 7957362

Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.

J T Li1, S G Shu, C S Chi.   

Abstract

We report a rare case of primary hyperaldosteronism in an 11-year-old female patient due to a unilateral adrenal cortical adenoma. The patient presented with hypertension, hypokalaemia and metabolic alkalosis associated with inappropriate kaliuresis. The diagnosis was supported by the following laboratory findings: elevated plasma aldosterone, suppressed plasma renin activity, nonsuppressible aldosterone secretion following saline infusion and absent plasma aldosterone response to ambulation. MRI revealed a 1 cm diameter adrenal tumour on the left side. Even though the NP-59 scintigraphy gave a negative result, laparotomy with left adrenalectomy was performed. Pathological examination confirmed an adenoma in the adrenal cortex. The patient's blood pressure and biochemical laboratory data normalized postoperatively within 2 days. We recommended that in hypertensive children with hypokalaemia and metabolic alkalosis, primary aldosteronism should be considered.

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Year:  1994        PMID: 7957362     DOI: 10.1007/BF01957000

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  8 in total

1.  Aldosteronism and hypertension. Primary aldosteronism versus hypertensive disease with secondary aldosteronism.

Authors:  J W CONN
Journal:  Arch Intern Med       Date:  1961-06

2.  I-131 NP-59 adrenal cortical scintigraphy in suspected primary aldosteronism.

Authors:  C H Kao; S Q Liao; S J Wang; M S Lin; C Y Hsu; W Y Lin
Journal:  Gaoxiong Yi Xue Ke Xue Za Zhi       Date:  1992-04

3.  A calcified aldosterone-producing tumor in a hypertensive, normokalemic, prepubertal girl.

Authors:  R P Kelch; M H Connors; S L Kaplan; E G Biglieri; M M Grumbach
Journal:  J Pediatr       Date:  1973-09       Impact factor: 4.406

Review 4.  Primary aldosteronism: diagnosis and treatment.

Authors:  W F Young; M J Hogan; G G Klee; C S Grant; J A van Heerden
Journal:  Mayo Clin Proc       Date:  1990-01       Impact factor: 7.616

5.  Aldosteronoma in a child with localization by adrenal vein aldosterone: collective review of the literature.

Authors:  G Kafrouni; M D Oakes; A N Lurvey; V DeQuattro
Journal:  J Pediatr Surg       Date:  1975-12       Impact factor: 2.545

6.  Hypertension caused by an aldosterone-secreting adenoma. Occurrence in a 7-year-old child.

Authors:  M Bryer-Ash; D M Wilson; B M Tune; R G Rosenfeld; S J Shochat; J A Luetscher
Journal:  Am J Dis Child       Date:  1984-07

7.  Childhood primary aldosteronism due to an adrenal adenoma: preoperative localization by adrenal vein catheterization.

Authors:  A Ganguly; J Bergstein; C E Grim; M N Yum; M H Weinberger
Journal:  Pediatrics       Date:  1980-03       Impact factor: 7.124

Review 8.  Scintigraphic studies in adrenal hypertension.

Authors:  M D Gross; B Shapiro
Journal:  Semin Nucl Med       Date:  1989-04       Impact factor: 4.446

  8 in total
  1 in total

Review 1.  Aldosteronoma in children: a partial review of the literature.

Authors:  T Decsi; G Soltész
Journal:  Eur J Pediatr       Date:  1995-03       Impact factor: 3.183

  1 in total

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