| Literature DB >> 7956363 |
A L George1, T A Varkony, H A Drabkin, J Han, J F Knops, W H Finley, G B Brown, D C Ward, M Haas.
Abstract
The chromosomal location of SCN5A, the gene encoding the principal voltage-gated Na+ channel expressed in human heart, has been determined by three independent methodologies: somatic cell hybrid mapping, chromosomal microdissection-polymerase chain reaction, and fluorescence in situ hybridization. The SCN5A gene was assigned to the short arm of chromosome 3 (band 3p21) by all three approaches. These data are further evidence that striated muscle Na+ channel genes are dispersed in the genome.Entities:
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Year: 1995 PMID: 7956363 DOI: 10.1159/000133892
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN: 0301-0171