| Literature DB >> 7954737 |
P Montagna1, P Cortelli, B Barbiroli.
Abstract
We describe the method of 31phosphorous magnetic resonance spectroscopy and review the results when it is applied to the study of brain and muscle energy metabolism in migraine subjects. Brain energy metabolism appears to be abnormal in all major subtypes of migraine when measured both during and between attacks. Impaired energy metabolism is also documented in skeletal muscle. We suggest that migraine is associated with a generalized disorder of mitochondrial oxidative phosphorylation and that this may constitute a threshold for the triggering of migraine attacks.Entities:
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Year: 1994 PMID： 7954737 DOI： 10.1046/j.1468-2982.1994.014003184.x
Source DB: PubMed Journal: Cephalalgia ISSN： 0333-1024 Impact factor: 6.292