Literature DB >> 7953570

Axis determination. Proteolytic generation of a morphogen.

S Roth1.   

Abstract

Ventral activation of a transmembrane receptor, Toll, is a crucial step in dorsoventral axis establishment in Drosophila embryos. The ventral ligand for Toll seems to be a proteolytic fragment of the Spätzle protein.

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Year:  1994        PMID: 7953570     DOI: 10.1016/s0960-9822(00)00170-6

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  7 in total

1.  Interallelic complementation at the Drosophila melanogaster gastrulation defective locus defines discrete functional domains of the protein.

Authors:  G Ponomareff; H Giordano; Y DeLotto; R DeLotto
Journal:  Genetics       Date:  2001-10       Impact factor: 4.562

2.  Autoproteolysis and feedback in a protease cascade directing Drosophila dorsal-ventral cell fate.

Authors:  M Dissing; H Giordano; R DeLotto
Journal:  EMBO J       Date:  2001-05-15       Impact factor: 11.598

Review 3.  Gene regulatory networks for development.

Authors:  Michael Levine; Eric H Davidson
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-23       Impact factor: 11.205

4.  Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.

Authors:  A Bergner; V Oganessyan; T Muta; S Iwanaga; D Typke; R Huber; W Bode
Journal:  EMBO J       Date:  1996-12-16       Impact factor: 11.598

5.  The dorsal protein enhances the biosynthesis and stability of the Drosophila I kappa B homologue cactus.

Authors:  K Kubota; N J Gay
Journal:  Nucleic Acids Res       Date:  1995-08-25       Impact factor: 16.971

6.  Gastrulation defective, a complement factor C2/B-like protease, interprets a ventral prepattern in Drosophila.

Authors:  R DeLotto
Journal:  EMBO Rep       Date:  2001-08       Impact factor: 8.807

Review 7.  A clear and present danger: endogenous ligands of Toll-like receptors.

Authors:  Jacob A Sloane; Daina Blitz; Zachary Margolin; Timothy Vartanian
Journal:  Neuromolecular Med       Date:  2009-10-14       Impact factor: 3.843

  7 in total

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