Literature DB >> 7951056

On the role of ADP to increase the inhibitory effect of cyclosporin on mitochondrial membrane permeability transition.

C Zazueta1, H Reyes-Vivas, N Corona, C Bravo, E Chávez.   

Abstract

This work reports an investigation which demonstrate that the addition of ADP is necessary to attain the protective effect of cyclosporin on the carboxyatractyloside-induced mitochondrial Ca2+ release. Evidence are presented which indicate that the effect of ADP is exerted by increasing the inhibitory action of cyclosporin on the enzyme cyclophilin.

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Year:  1994        PMID： 7951056

Source DB:  PubMed          Journal:  Biochem Mol Biol Int        ISSN： 1039-9712


  3 in total

1.  On the protection by inorganic phosphate of calcium-induced membrane permeability transition.

Authors:  E Chávez; R Moreno-Sánchez; C Zazueta; J S Rodríguez; C Bravo; H Reyes-Vivas
Journal:  J Bioenerg Biomembr       Date:  1997-12       Impact factor: 2.945

2.  Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.

Authors:  S Schuchmann; W Müller; U Heinemann
Journal:  J Neurosci       Date:  1998-09-15       Impact factor: 6.167

3.  The composition of the incubation medium influences the sensitivity of mitochondrial permeability transition to cyclosporin A.

Authors:  Edmundo Chávez; Noemi García; Cecilia Zazueta; Francisco Correa; César Avilés; Gerardo García; Eros O Balam
Journal:  J Bioenerg Biomembr       Date:  2003-04       Impact factor: 2.945
  3 in total

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