Literature DB >> 7950963

Regulation of BDNF promoters in the rat hippocampus.

T Timmusk1, M Metsis.   

Abstract

Brain-derived neurotrophic factor belongs to the neurotrophin family of trophic factors. Recently we have described four promoters in the BDNF gene. We have analyzed the hippocampal expression pattern of BDNF mRNA's containing different 5' exons during postnatal development. This analysis has revealed distinct regulation of promoters I and II compared to promoters III and IV, which suggests the presence of common regulatory elements for these clusters of promoters. Induction of different BDNF promoters after treatment with kainic acid combined with glutamate antagonists MK801 and NBQX discloses the differential participation of different glutamate receptor subtypes in regulation of the BDNF gene in the hippocampus.

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Year:  1994        PMID： 7950963     DOI： 10.1016/0197-0186(94)90046-9

Source DB:  PubMed          Journal:  Neurochem Int        ISSN： 0197-0186            Impact factor:   3.921


  7 in total

1.  Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone.

Authors:  Y Dwivedi; H S Rizavi; G N Pandey
Journal:  Neuroscience       Date:  2006-02-24       Impact factor: 3.590

2.  Darkness reduces BDNF expression in the visual cortex and induces repressive chromatin remodeling at the BDNF gene in both hippocampus and visual cortex.

Authors:  Nina N Karpova; Tomi Rantamäki; Antonio Di Lieto; Lothar Lindemann; Marius C Hoener; Eero Castrén
Journal:  Cell Mol Neurobiol       Date:  2010-07-08       Impact factor: 5.046

3.  Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research.

Authors:  Galit Weinstein; Sarah R Preis; Alexa S Beiser; Bernhard Kaess; Tai C Chen; Claudia Satizabal; Faisal Rahman; Emelia J Benjamin; Ramachandran S Vasan; Sudha Seshadri
Journal:  Curr Alzheimer Res       Date:  2017       Impact factor: 3.498

4.  Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats.

Authors:  Gretha J Boersma; Richard S Lee; Zachary A Cordner; Erin R Ewald; Ryan H Purcell; Alexander A Moghadam; Kellie L Tamashiro
Journal:  Epigenetics       Date:  2013-12-23       Impact factor: 4.528

5.  HIV-1 Tat protein promotes neuronal dysregulation by inhibiting E2F transcription factor 3 (E2F3).

Authors:  Maryline Santerre; Asen Bagashev; Laura Gorecki; Kyle Z Lysek; Ying Wang; Jenny Shrestha; Fabiola Del Carpio-Cano; Ruma Mukerjee; Bassel E Sawaya
Journal:  J Biol Chem       Date:  2018-12-27       Impact factor: 5.157

6.  HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons.

Authors:  Amir Bagheri; Parham Habibzadeh; Seyedeh Fatemeh Razavipour; Claude-Henry Volmar; Nancy T Chee; Shaun P Brothers; Claes Wahlestedt; Seyed Javad Mowla; Mohammad Ali Faghihi
Journal:  Int J Mol Sci       Date:  2019-03-05       Impact factor: 5.923

7.  TrkB Truncated Isoform Receptors as Transducers and Determinants of BDNF Functions.

Authors:  Lino Tessarollo; Sudhirkumar Yanpallewar
Journal:  Front Neurosci       Date:  2022-03-07       Impact factor: 4.677
  7 in total

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