Chordal reconstruction with polytetrafluoroethylene (PTFE) sutures for mitral regurgitation.

Chordal reconstruction of the mitral valve using CV4 or CV5 polytetrafluoroethylene (PTFE) (Gore-Tex. Flagstaff, AZ, USA) sutures was performed in seven patients with mitral regurgitation (MR) to ascertain its efficacy. The MR had been caused by prolapse of the anterior leaflet in three patients, the posterior leaflet in two, and both leaflets in two; five of the patients had an MR of grade III or IV. There was one hospital death, which occurred in a patient whose MR had resulted from papillary muscle dysfunction caused by a myocardial infarction (MI). Chordal reconstruction failed and was converted to a mitral valve replacement in two patients, one of whom had suffered a MI and another who had a congenital papillary muscle anomaly. The remaining five patients all underwent successful chordal reconstruction with PTFE sutures, resulting in the disappearance of the MR in two patients and an improvement to grade I in three patients. Although the longest follow-up period has been only 1 year, the MR has not worsened. This technique is relatively easy to perform, and allows almost all the mitral apparatus to remain in situ, while enabling repair of the mitral valve, regardless of the state of the diseased chordae.