Literature DB >> 7947474

The synthesis of a water soluble complement activating polyacrylic acid-IgG polymer.

G Schmer1, R A Henderson, W Müller.   

Abstract

Polyacrylic acid-IgG polymer (PAA-IgG) activates the classical and alternative pathway of complement as shown by specific Clq-(IgG-PAA) interaction and the generation of C4d, Bb, C3b, C3a and C5a. This water soluble and stable PAA-IgG polymer represents a model substance for the study of humoral and cellular inflammatory mechanisms, mediated by the complement system.

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Year:  1994        PMID: 7947474     DOI: 10.1163/156856295x00760

Source DB:  PubMed          Journal:  J Biomater Sci Polym Ed        ISSN: 0920-5063            Impact factor:   3.517


  2 in total

1.  Complement activation by gold nanoparticles passivated with polyelectrolyte ligands.

Authors:  Quang Huy Quach; James Chen Kah
Journal:  RSC Adv       Date:  2018-02-09       Impact factor: 4.036

Review 2.  Intramolecular immunological signal hypothesis revived--structural background of signalling revealed by using Congo Red as a specific tool.

Authors:  A Jagusiak; L Konieczny; M Krol; P Marszalek; B Piekarska; P Piwowar; I Roterman; J Rybarska; B Stopa; G Zemanek
Journal:  Mini Rev Med Chem       Date:  2015       Impact factor: 3.862

  2 in total

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