| Literature DB >> 7946244 |
Abstract
Females have stronger immune responses than males. Female predominance in autoimmune diseases in both experimental animals and in man is also established. Sex hormones and some other steroid hormones have been shown to exert immunoregulatory effects in both in vivo and in vitro situations. Important mechanisms of hormone action on lymphocytes have gradually been revealed. In this paper the most intriguing effects of steroid hormones on immune system and present data suggesting hormonal influence on the pathogenesis of autoimmune diseases are summarized.Entities:
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Year: 1994 PMID: 7946244 DOI: 10.3109/07853899409147900
Source DB: PubMed Journal: Ann Med ISSN: 0785-3890 Impact factor: 4.709