Literature DB >> 7945719

Antibacterial activity of metal complexes of benzil and benzoin thiosemicarbazones.

O E Offiong1, S Martelli.   

Abstract

The metal (II) complexes of benzyl and benzoin thiosemicarbazones have been synthesized and characterized. They were studied for their antibacterial, antifungal and amoebicidal activity in vitro and for their toxicity in vivo. The ligands and their metal complexes exhibited low antibacterial and amoebicidal activity. The metal chelates of benzoin thiosemicarbazone seem to be the most active compounds.

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Year:  1994        PMID： 7945719

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  6 in total

1.  Microwave synthesis of mixed ligand diimine-thiosemicarbazone complexes of ruthenium(II): biophysical reactivity and cytotoxicity.

Authors:  Floyd A Beckford; Michael Shaloski; Gabriel Leblanc; Jeffrey Thessing; Lesley C Lewis-Alleyne; Alvin A Holder; Liya Li; Navindra P Seeram
Journal:  Dalton Trans       Date:  2009-09-28       Impact factor: 4.390

2.  Synthesis and structure of [(η(6)-p-cymene)Ru(2-anthracen-9-ylmethylene-N-ethylhydrazinecarbothioamide)Cl]Cl; biological evaluation, topoisomerase II inhibition and reaction with DNA and human serum albumin.

Authors:  Floyd Beckford; Jeffrey Thessing; Jason Woods; Jacob Didion; Nikolay Gerasimchuk; Antonio Gonzalez-Sarrias; Navindra P Seeram
Journal:  Metallomics       Date:  2011-02-23       Impact factor: 4.526

3.  Cytotoxic gallium complexes containing thiosemicarbazones derived from 9-anthraldehyde: Molecular docking with biomolecules.

Authors:  Floyd A Beckford; Alyssa Brock; Antonio Gonzalez-Sarrías; Navindra P Seeram
Journal:  J Mol Struct       Date:  2016-05-24       Impact factor: 3.196

4.  Half-sandwich ruthenium–arene complexes with thiosemicarbazones: synthesis and biological evaluation of [(η⁶-p-cymene)Ru(piperonal thiosemicarbazones)Cl]Cl complexes.

Authors:  Floyd Beckford; Deidra Dourth; Michael Shaloski; Jacob Didion; Jeffrey Thessing; Jason Woods; Vernon Crowell; Nikolay Gerasimchuk; Antonio Gonzalez-Sarrías; Navindra P Seeram
Journal:  J Inorg Biochem       Date:  2011-08       Impact factor: 4.155

5.  Synthesis and characterization of mixed-ligand diimine-piperonal thiosemicarbazone complexes of ruthenium(II): Biophysical investigations and biological evaluation as anticancer and antibacterial agents.

Authors:  Floyd A Beckford; Jeffrey Thessing; Michael Shaloski; P Canisius Mbarushimana; Alyssa Brock; Jacob Didion; Jason Woods; Antonio Gonzalez-Sarrías; Navindra P Seeram
Journal:  J Mol Struct       Date:  2011-04-19       Impact factor: 3.196

6.  Antimicrobial activity of a series of thiosemicarbazones and their Zn(II) and Pd(II) complexes.

Authors:  I Kizilcikli; Y D Kurt; B Akkurt; A Y Genel; S Birteksöz; G Otük; B Ulküseven
Journal:  Folia Microbiol (Praha)       Date:  2007       Impact factor: 2.629
  6 in total

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