Literature DB >> 7944689

Severe calcification does not affect long-term outcome of mitral valve repair.

E A Grossi1, A C Galloway, B M Steinberg, M LeBoutillier, J Delianides, F G Baumann, F C Spencer, S B Colvin.   

Abstract

Some surgeons have suggested that the presence of severe calcification in the mitral valve annulus or leaflets precludes successful repair. Our institution has attempted to repair these calcified valves when good annular and leaflet mobility could be achieved by annular debridement and leaflet resection. From June 1979 through June 1993 558 mitral valve repairs were performed using Carpentier's techniques. When calcified valves were encountered, these techniques were modified to include annular debridement and mechanical leaflet decalcification. Calcification was identified preoperatively in 49 patients (8.8%) by either left ventricular fluoroscopy or echocardiography and was debrided in 64 patients (11.5%). This included 24 annular debridements, 28 leaflet debridements, and 12 annular and leaflet debridements. Patient ages ranged from 13 to 83 years (mean age, 62.3 years), and 25 patients (39.1%, 25/64) had concomitant cardiac procedures. Operative mortality was 6.2% (4/64) overall and 2.6% (1/39) for isolated mitral valve repairs. Calcium debridement was performed in 19.3% (23/119) of patients with a rheumatic cause compared with 9.3% (41/439) of the nonrheumatic patients (p < 0.01). Long-term follow-up revealed the necessity for reoperation in 7.8% (5/64) in patients with calcium debridement as compared with 7.7% (38/494) with no debridement (p = not significant). Cumulative freedom from reoperation at 10 years was 83.3% for all patients, 88.1% for debrided patients, and 82.6% for nondebrided patients (p = not significant). Cox proportional hazards analysis revealed that the presence of rheumatic disease significantly increased the risk of reoperation (odds ratio = 3.28; p < 0.001), whereas calcium debridement had no significant effect. These results demonstrate that when good annulus and leaflet motion can be achieved in calcified mitral valves, calcium debridement allows durable repairs.

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Year:  1994        PMID: 7944689     DOI: 10.1016/0003-4975(94)90728-5

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  4 in total

Review 1.  Mitral annular calcification: challenges and future perspectives.

Authors:  Mathias Van Hemelrijck; Maurizio Taramasso; Gökhan Gülmez; Francesco Maisano; Carlos-A Mestres
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2020-01-27

2.  Severe mitral annular calcification in rheumatic heart disease: A rare presentation.

Authors:  Rajesh Vijayvergiya; Kim Vaiphei; Sandeep S Rana
Journal:  World J Cardiol       Date:  2012-03-26

Review 3.  Mitral valve repair versus replacement.

Authors:  Stephanie L Mick; Suresh Keshavamurthy; A Marc Gillinov
Journal:  Ann Cardiothorac Surg       Date:  2015-05

4.  Modified transventricular and transaortic mitral valve edge-to-edge repair mimicking MitraClip overcorrection.

Authors:  Nestoras Papadopoulos; Omer Dzemali; Luisa Bott; Vasileios Ntinopoulos; Aleksandra Miskovic; Anton Moritz
Journal:  JTCVS Tech       Date:  2022-01-19
  4 in total

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