Literature DB >> 7940982

Long-circulating (sterically stabilized) liposomes for targeted drug delivery.

T M Allen1.   

Abstract

Anticancer chemotherapy is limited by adverse side-effects resulting from toxicities to normal tissues. Targeted delivery of drugs to diseased tissues in vivo would help to reduce these side-effects. Liposomes containing lipid derivatives of polyethylene glycol (sterically stabilized liposomes) have circulation times that are sufficiently long to allow for effective in vivo drug delivery, and are discussed in this review by Theresa Allen. Sterically stabilized liposomes, containing entrapped doxorubicin, targeted to squamous cell lung carcinoma by means of specific antibodies attached at the liposome surface are capable of reducing tumour burden to a significant extent and eradicating tumour in a significant percentage of mice.

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Year:  1994        PMID： 7940982     DOI： 10.1016/0165-6147(94)90314-x

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  70 in total

Review 1.  Drug transport to brain with targeted liposomes.

Authors:  Anita Schnyder; Jörg Huwyler
Journal:  NeuroRx       Date:  2005-01

Review 2.  Anti-tumor gene therapy.

Authors:  C Cirielli; M C Capogrossi; A Passaniti
Journal:  J Neurooncol       Date:  1997-01       Impact factor: 4.130

Review 3.  Perspectives and opportunities for nanomedicine in the management of atherosclerosis.

Authors:  Mark E Lobatto; Valentin Fuster; Zahi A Fayad; Willem J M Mulder
Journal:  Nat Rev Drug Discov       Date:  2011-10-21       Impact factor: 84.694

4.  Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer.

Authors:  M T Peracchia; C Vauthier; D Desmaële; A Gulik; J C Dedieu; M Demoy; J d'Angelo; P Couvreur
Journal:  Pharm Res       Date:  1998-04       Impact factor: 4.200

Review 5.  Disposition of drugs in block copolymer micelle delivery systems: from discovery to recovery.

Authors:  Hamidreza Montazeri Aliabadi; Mostafa Shahin; Dion R Brocks; Afsaneh Lavasanifar
Journal:  Clin Pharmacokinet       Date:  2008       Impact factor: 6.447

6.  Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.

Authors:  J A Kamps; H W Morselt; P J Swart; D K Meijer; G L Scherphof
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

7.  Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs.

Authors:  E Merisko-Liversidge; P Sarpotdar; J Bruno; S Hajj; L Wei; N Peltier; J Rake; J M Shaw; S Pugh; L Polin; J Jones; T Corbett; E Cooper; G G Liversidge
Journal:  Pharm Res       Date:  1996-02       Impact factor: 4.200

8.  Targeting of skeletal muscle in vitro using biotinylated immunoliposomes.

Authors:  Anita Schnyder; Stefan Krähenbühl; Michael Török; Jürgen Drewe; Jörg Huwyler
Journal:  Biochem J       Date:  2004-01-01       Impact factor: 3.857

9.  How well does cholesteryl hemisuccinate mimic cholesterol in saturated phospholipid bilayers?

Authors:  Waldemar Kulig; Joona Tynkkynen; Matti Javanainen; Moutusi Manna; Tomasz Rog; Ilpo Vattulainen; Pavel Jungwirth
Journal:  J Mol Model       Date:  2014-02-14       Impact factor: 1.810

10.  Tumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models.

Authors:  Dan Peer; Rimona Margalit
Journal:  Neoplasia       Date:  2004 Jul-Aug       Impact factor: 5.715
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