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Literature DB >> 793957

Immune response to phi X 174 in man. 5. Primary and secondary antibody production in primary biliary cirrhosis.

H C Thomas, R Holden, J V Jones, D B Peacock.

Abstract

In primary biliary cirrhosis, the primary immune response to the bacteriophage phi X 174 is normal but the secondary response is significantly reduced. The reduction is primarily of IgG antibody, while IgM is proportionately less affected. These changes may be the result of a reduction in helper T lymphocyte function and may contribute to the increase in the ratio of serum concentration of IgM to IgG.

Entities: Disease Species

Mesh：

Substances：

Year: 1976 PMID： 793957 PMCID： PMC1411209 DOI： 10.1136/gut.17.11.844

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

12 in total

1. The production of antibody by partially hepatectomized rats.

Authors: W P HAVENS; M E SCHLOSSER; J KLATCHKO
Journal: J Immunol Date: 1956-01 Impact factor: 5.422

2. The production of antibody by patients with chronic hepatic disease.

Authors: W P HAVENS; J M SHAFFER; C J HOPKE
Journal: J Immunol Date: 1951-10 Impact factor: 5.422

3. Antibodies to intestinal microbes in serum of patients with cirrhosis of the liver.

Authors: M Bjorneboe; H Prytz; F Orskov
Journal: Lancet Date: 1972-01-08 Impact factor: 79.321

4. The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults.

Authors: D B Peacock; J V Jones; M Gough
Journal: Clin Exp Immunol Date: 1973-04 Impact factor: 4.330

5. Impaired delayed hypersensitivity in primary biliary cirrhosis.

Authors: S Sherlock; R A Fox; D G James; P J Scheuer; O Sharma
Journal: Lancet Date: 1969-05-10 Impact factor: 79.321

6. Effect of host decomplementation on homeostasis of antibody production in fowl.

Authors: K H Nielsen; R G White
Journal: Nature Date: 1974-07-19 Impact factor: 49.962

7. Phytohaemagglutinin (PHA) induced lymphocyte transformation and Toxoplasma gondii antibody studies in primary biliary cirrhosis. Evidence of impaired cell-mediated immunity.

Authors: R N MacSween; I Galbraith; M A Thomas; G Watkinson; G B Ludlam
Journal: Clin Exp Immunol Date: 1973-09 Impact factor: 4.330

8. Primary biliary cirrhosis.

Authors: P Scheuer
Journal: Proc R Soc Med Date: 1967-12

9. The immune response of phiX 174 in man. III. Evidence for an association between hyposplenism and immunodeficiency in patients with coeliac disease.

Authors: P G Baker; J V Jones; D B Peacock; A E Read
Journal: Gut Date: 1975-07 Impact factor: 23.059

10. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Authors: M Jondal; G Holm; H Wigzell
Journal: J Exp Med Date: 1972-08-01 Impact factor: 14.307

9 in total

Review 1. Comprehensive review of autoantibodies in patients with hyper-IgM syndrome.

Authors: Mohamed-Ridha Barbouche; Qubo Chen; Marco Carbone; Imen Ben-Mustapha; Zakera Shums; Mehdi Trifa; Federica Malinverno; Francesca Bernuzzi; Haiyan Zhang; Nourhen Agrebi; Gary L Norman; Christopher Chang; M Eric Gershwin; Pietro Invernizzi
Journal: Cell Mol Immunol Date: 2018-02-05 Impact factor: 11.530

Immune response to phi X 174 in man. 5. Primary and secondary antibody production in primary biliary cirrhosis.

1. The production of antibody by partially hepatectomized rats.

2. The production of antibody by patients with chronic hepatic disease.

3. Antibodies to intestinal microbes in serum of patients with cirrhosis of the liver.

4. The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults.

5. Impaired delayed hypersensitivity in primary biliary cirrhosis.

6. Effect of host decomplementation on homeostasis of antibody production in fowl.

7. Phytohaemagglutinin (PHA) induced lymphocyte transformation and Toxoplasma gondii antibody studies in primary biliary cirrhosis. Evidence of impaired cell-mediated immunity.

8. Primary biliary cirrhosis.

9. The immune response of phiX 174 in man. III. Evidence for an association between hyposplenism and immunodeficiency in patients with coeliac disease.

10. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Review 1. Comprehensive review of autoantibodies in patients with hyper-IgM syndrome.

2. Interstitial lung disease and Sjögren's syndrome in primary biliary cirrhosis: a causal or casual association?

3. The immune response in hepatic cirrhosis: animal and human studies.

4. Antibody responses to tetanus toxoid in patients with primary biliary cirrhosis.

Review 5. Pathogenic mechanisms in primary biliary cirrhosis.

6. Lymphocyte populations in liver biopsy specimens from patients with chronic liver disease.

7. In vitro studies on the mechanism of increased serum IgM levels in primary biliary cirrhosis.

8. Circulating activated B cells in primary biliary cirrhosis.

9. Alterations of T-cell subsets in primary biliary cirrhosis.