Literature DB >> 7937983

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

I Ingelbrecht1, H Van Houdt, M Van Montagu, A Depicker.   

Abstract

Endogenous plant genes or transgenes can be silenced on introduction of homologous gene sequences. Here we document a reporter gene-silencing event in Nicotiana tabacum that has a distinctive combination of features--i.e., (i) silencing occurs by a posttranscriptional process, (ii) silencing correlates with DNA methylation, and (iii) this de novo methylation is not restricted to cytosines located in the symmetrical motifs CG and CXG.

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Year:  1994        PMID: 7937983      PMCID: PMC45049          DOI: 10.1073/pnas.91.22.10502

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  44 in total

1.  The effect of T-DNA copy number, position and methylation on reporter gene expression in tobacco transformants.

Authors:  S L Hobbs; P Kpodar; C M DeLong
Journal:  Plant Mol Biol       Date:  1990-12       Impact factor: 4.076

2.  Differential inactivation and methylation of a transgene in plants by two suppressor loci containing homologous sequences.

Authors:  M A Matzke; A J Matzke
Journal:  Plant Mol Biol       Date:  1991-05       Impact factor: 4.076

3.  Allelic interactions at the nivea locus of Antirrhinum.

Authors:  J Bollmann; R Carpenter; E S Coen
Journal:  Plant Cell       Date:  1991-12       Impact factor: 11.277

4.  Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors.

Authors:  P B Becker; S Ruppert; G Schütz
Journal:  Cell       Date:  1987-11-06       Impact factor: 41.582

5.  Differences in DNA-methylation are associated with a paramutation phenomenon in transgenic petunia.

Authors:  P Meyer; I Heidmann; I Niedenhof
Journal:  Plant J       Date:  1993-07       Impact factor: 6.417

6.  Coordinate suppression of mutations caused by Robertson's mutator transposons in maize.

Authors:  R Martienssen; A Baron
Journal:  Genetics       Date:  1994-03       Impact factor: 4.562

7.  Substrate and sequence specificity of a eukaryotic DNA methylase.

Authors:  Y Gruenbaum; H Cedar; A Razin
Journal:  Nature       Date:  1982-02-18       Impact factor: 49.962

Review 8.  Premeiotic instability of repeated sequences in Neurospora crassa.

Authors:  E U Selker
Journal:  Annu Rev Genet       Date:  1990       Impact factor: 16.830

9.  Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

Authors:  J Boyes; A Bird
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

10.  Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida.

Authors:  P Meyer; I Niedenhof; M ten Lohuis
Journal:  EMBO J       Date:  1994-05-01       Impact factor: 11.598

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  81 in total

1.  RNA-DNA interactions and DNA methylation in post-transcriptional gene silencing.

Authors:  L Jones; A J Hamilton; O Voinnet; C L Thomas; A J Maule; D C Baulcombe
Journal:  Plant Cell       Date:  1999-12       Impact factor: 11.277

2.  A DNA target of 30 bp is sufficient for RNA-directed DNA methylation.

Authors:  T Pélissier; M Wassenegger
Journal:  RNA       Date:  2000-01       Impact factor: 4.942

3.  Expression of a yeast RNase III gene in transgenic tobacco silences host nitrite reductase genes.

Authors:  R Berthomé; P Y Teycheney; J P Renou; Y Okada; M Tepfer
Journal:  Plant Mol Biol       Date:  2000-09       Impact factor: 4.076

4.  Mum's the word: MOM and modifiers of transcriptional gene silencing.

Authors:  T L Stokes; E J Richards
Journal:  Plant Cell       Date:  2000-07       Impact factor: 11.277

Review 5.  The rest is silence.

Authors:  E Bernstein; A M Denli; G J Hannon
Journal:  RNA       Date:  2001-11       Impact factor: 4.942

Review 6.  RNA degradation and models for post-transcriptional gene-silencing.

Authors:  F Meins
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 7.  RNA-directed DNA methylation.

Authors:  M Wassenegger
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 8.  RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing.

Authors:  R Marathe; R Anandalakshmi; T H Smith; G J Pruss; V B Vance
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 9.  Transgene silencing in monocots.

Authors:  L M Iyer; S P Kumpatla; M B Chandrasekharan; T C Hall
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

Review 10.  Paramutation in maize.

Authors:  V L Chandler; W B Eggleston; J E Dorweiler
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

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