Literature DB >> 7937114

New restriction endonuclease CviRI cleaves DNA at TG/CA sequences.

A Jin1, Y Zhang, Y Xia, E Traylor, M Nelson, J L Van Etten.   

Abstract

A new type II restriction endonuclease, CviRI, was isolated from virus XZ-6E infected chlorella cells. CviRI is the first restriction endonuclease to recognize the sequence 5'-TGCA-3' and cleaves DNA between the G and C residues to produce blunt-end termini. Methylation of the adenine or cytosine in 5'-TGCA-3' sequences prevents CviRI cleavage. Due to its sequence specificity, CviRI may be especially useful for detecting mutant alleles of many heritable human genetic diseases.

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Year:  1994        PMID: 7937114      PMCID: PMC308391          DOI: 10.1093/nar/22.19.3928

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  11 in total

1.  Molecular cloning and characterization of the gene encoding the adenine methyltransferase M.CviRI from Chlorella virus XZ-6E.

Authors:  C Stefan; Y N Xia; J L Van Etten
Journal:  Nucleic Acids Res       Date:  1991-01-25       Impact factor: 16.971

2.  The CpG dinucleotide and human genetic disease.

Authors:  D N Cooper; H Youssoufian
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

3.  5-Methylcytosine replacing cytosine in the deoxyribonucleic acid of a bacteriophage for Xanthomonas oryzae.

Authors:  T T Kuo; T C Huang; M H Teng
Journal:  J Mol Biol       Date:  1968-07-14       Impact factor: 5.469

Review 4.  DNA polymorphism and the study of disease associations.

Authors:  D N Cooper; J F Clayton
Journal:  Hum Genet       Date:  1988-04       Impact factor: 4.132

5.  Restriction endonuclease activity induced by PBCV-1 virus infection of a Chlorella-like green alga.

Authors:  Y N Xia; D E Burbank; L Uher; D Rabussay; J L Van Etten
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

6.  5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes.

Authors:  W M Rideout; G A Coetzee; A F Olumi; P A Jones
Journal:  Science       Date:  1990-09-14       Impact factor: 47.728

7.  Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3. Structure and genetics of an apolipoprotein E3 variant.

Authors:  S C Rall; Y M Newhouse; H R Clarke; K H Weisgraber; B J McCarthy; R W Mahley; T P Bersot
Journal:  J Clin Invest       Date:  1989-04       Impact factor: 14.808

8.  CpG mutations in the reactive site of human C1 inhibitor.

Authors:  K Skriver; E Radziejewska; J A Silbermann; V H Donaldson; S C Bock
Journal:  J Biol Chem       Date:  1989-02-25       Impact factor: 5.157

9.  Identification of a point mutation in the adenosine deaminase gene responsible for immunodeficiency.

Authors:  D T Bonthron; A F Markham; D Ginsburg; S H Orkin
Journal:  J Clin Invest       Date:  1985-08       Impact factor: 14.808

10.  Substitution of cysteine for glycine at residue 415 of one allele of the alpha 1(I) chain of type I procollagen in type III/IV osteogenesis imperfecta.

Authors:  A C Nicholls; J Oliver; D V Renouf; M Keston; F M Pope
Journal:  J Med Genet       Date:  1991-11       Impact factor: 6.318

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  1 in total

1.  A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

Authors:  E Y Krynetski; J D Schuetz; A J Galpin; C H Pui; M V Relling; W E Evans
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-14       Impact factor: 11.205

  1 in total

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