Literature DB >> 7934844

Secondary-sites for integration mediated by the Tn21 integrase.

M V Francia1, F de la Cruz, J M García Lobo.   

Abstract

The integrase encoded by the integron of the transposon Tn21 can mediate the site-specific fusion of two plasmids if there is a recombination hot spot (59 bp element) in one of them and the sequence GWTMW in the other. The use of this latter, loosely defined site explains how antibiotic-resistance genes could first become associated with integrons.

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Year:  1993        PMID： 7934844     DOI： 10.1111/j.1365-2958.1993.tb00952.x

Source DB:  PubMed          Journal:  Mol Microbiol        ISSN： 0950-382X            Impact factor:   3.501


  22 in total

1.  Identification of a complete dfrA14 gene cassette integrated at a secondary site in a resistance plasmid of uropathogenic Escherichia coli from Nigeria.

Authors:  Kayode K Ojo; Corinna Kehrenberg; Stefan Schwarz; H Akin Odelola
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

2.  Efficiency of recombination reactions catalyzed by class 1 integron integrase IntI1.

Authors:  C M Collis; G D Recchia; M J Kim; H W Stokes; R M Hall
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

3.  Novel rearrangement of a class 2 integron in two non-epidemiologically related isolates of Acinetobacter baumannii.

Authors:  María Soledad Ramírez; Cecilia Quiroga; Daniela Centrón
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

4.  A hot spot in plasmid F for site-specific recombination mediated by Tn21 integron integrase.

Authors:  M V Francia; P Avila; F de la Cruz; J M García Lobo
Journal:  J Bacteriol       Date:  1997-07       Impact factor: 3.490

5.  Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids.

Authors:  Carlos Revilla; M Pilar Garcillán-Barcia; Raúl Fernández-López; Nicholas R Thomson; Mandy Sanders; Martin Cheung; Christopher M Thomas; Fernando de la Cruz
Journal:  Antimicrob Agents Chemother       Date:  2008-02-11       Impact factor: 5.191

6.  Worldwide prevalence of class 2 integrases outside the clinical setting is associated with human impact.

Authors:  Carlos M Rodríguez-Minguela; Juha H A Apajalahti; Benli Chai; James R Cole; James M Tiedje
Journal:  Appl Environ Microbiol       Date:  2009-06-05       Impact factor: 4.792

7.  Characterization of Class 1 integrons from Pseudomonas aeruginosa that contain the bla(VIM-2) carbapenem-hydrolyzing beta-lactamase gene and of two novel aminoglycoside resistance gene cassettes.

Authors:  L Poirel; T Lambert; S Türkoglü; E Ronco; J Gaillard; P Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2001-02       Impact factor: 5.191

8.  Molecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins.

Authors:  B Hochhut; Y Lotfi; D Mazel; S M Faruque; R Woodgate; M K Waldor
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

9.  Isolation of an integron-borne blaVIM-4 type metallo-beta-lactamase gene from a carbapenem-resistant Pseudomonas aeruginosa clinical isolate in Hungary.

Authors:  Balázs Libisch; Mária Gacs; Károly Csiszár; Mónika Muzslay; László Rókusz; Miklós Füzi
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

10.  The relaxed requirements of the integron cleavage site allow predictable changes in integron target specificity.

Authors:  Clara Frumerie; Magaly Ducos-Galand; Deshmukh N Gopaul; Didier Mazel
Journal:  Nucleic Acids Res       Date:  2009-11-13       Impact factor: 16.971
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