Literature DB >> 7934542

HLA and hepatitis B infection.

A Almarri1, J R Batchelor.   

Abstract

The mechanism underlying the development of chronic infection with hepatitis B virus is not known. We have done two independent studies in Qatar, where such infection is common, to determine whether immunity to this virus is influenced by the HLA phenotype of an individual. The first study generated a hypothesis to test in the second. In both studies, there was a significant deficiency of HLA-DR2 and an excess of HLA-DR7 in patients with chronic persistent infection with hepatitis B virus. We conclude that HLA phenotype is one of the factors influencing the response to infection with this virus.

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Year:  1994        PMID： 7934542     DOI： 10.1016/s0140-6736(94)90510-x

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  27 in total

1.  Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.

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2.  Pathogenic and protective correlates of T cell proliferation in AIDS. HNRC Group. HIV Neurobehavioral Research Center.

Authors:  R D Schrier; C A Wiley; C Spina; J A McCutchan; I Grant
Journal:  J Clin Invest       Date:  1996-08-01       Impact factor: 14.808

Review 3.  Neurocysticercosis and epilepsy in developing countries.

Authors:  D K Pal; A Carpio; J W Sander
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-02       Impact factor: 10.154

Review 4.  Current status and prospects of studies on human genetic alleles associated with hepatitis B virus infection.

Authors:  Fu-Sheng Wang
Journal:  World J Gastroenterol       Date:  2003-04       Impact factor: 5.742

Review 5.  Treatment of hepatitis B virus: an update.

Authors:  Haley Ward; Lydia Tang; Bhawna Poonia; Shyam Kottilil
Journal:  Future Microbiol       Date:  2016-11-18       Impact factor: 3.165

6.  Association of HLA class II genes with susceptibility to Crohn's disease.

Authors:  P M Danzé; J F Colombel; S Jacquot; M N Loste; D Heresbach; S Ategbo; S Khamassi; B Périchon; G Semana; D Charron; J P Cézard
Journal:  Gut       Date:  1996-07       Impact factor: 23.059

7.  Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients.

Authors:  S Mascheretti; H Hinrichsen; S Ross; P Buggisch; J Hampe; U R Foelsch; S Schreiber
Journal:  Clin Exp Immunol       Date:  2004-05       Impact factor: 4.330

8.  Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: mechanisms for viral immune escape.

Authors:  Susanne Beckebaum; Vito R Cicinnati; Xia Zhang; Stanislav Ferencik; Andrea Frilling; Hans Grosse-Wilde; Christoph Erich Broelsch; Guido Gerken
Journal:  Immunology       Date:  2003-08       Impact factor: 7.397

Review 9.  Regulation of major histocompatibility complex class II gene expression, genetic variation and disease.

Authors:  L Handunnetthi; S V Ramagopalan; G C Ebers; J C Knight
Journal:  Genes Immun       Date:  2009-11-05       Impact factor: 2.676

10.  Association of -238G/A polymorphism of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection in Chinese Han population.

Authors:  Liang-Ping Lu; Xing-Wang Li; Ying Liu; Guo-Chang Sun; Xue-Ping Wang; Xi-Lin Zhu; Quan-You Hu; Hui Li
Journal:  World J Gastroenterol       Date:  2004-06-15       Impact factor: 5.742
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