Literature DB >> 7932861

Molecular cloning and characterization of rat brain 2',3'-cyclic nucleotide 3'-phosphodiesterase isoform 2.

M Gravel1, D DeAngelis, P E Braun.   

Abstract

We have isolated a cDNA coding for the larger isoform of the rat brain 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP2), a protein associated with myelination in the central nervous system (CNS). The complete 420 amino acid sequence was deduced from the nucleotide sequence of the cDNA. Sequence comparisons show that rat CNP shares 96% homology with mouse, 84% with bovine, and 86% with human CNP. Errors in the published sequence of rat CNP1 have now been corrected. Comparisons with other proteins reveal several interesting conserved motifs, including two leucine repeat heptads, and two consensus motifs for phosphorylation in the N-terminal domain of CNP2.

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Year:  1994        PMID： 7932861     DOI： 10.1002/jnr.490380302

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN： 0360-4012            Impact factor:   4.164


  10 in total

1.  Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

Authors:  Matti Myllykoski; Petri Kursula
Journal:  BMC Res Notes       Date:  2010-01-21

Review 2.  The myelin membrane-associated enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase: on a highway to structure and function.

Authors:  Arne Raasakka; Petri Kursula
Journal:  Neurosci Bull       Date:  2014-05-07       Impact factor: 5.203

3.  Actin plays a role in both changes in cell shape and gene-expression associated with Schwann cell myelination.

Authors:  C Fernandez-Valle; D Gorman; A M Gomez; M B Bunge
Journal:  J Neurosci       Date:  1997-01-01       Impact factor: 6.167

4.  Oligodendrocyte-specific expression of human immunodeficiency virus type 1 Nef in transgenic mice leads to vacuolar myelopathy and alters oligodendrocyte phenotype in vitro.

Authors:  Fatiha Radja; Denis G Kay; Steffen Albrecht; Paul Jolicoeur
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103

5.  Identification and characterization of early glial progenitors using a transgenic selection strategy.

Authors:  K J Chandross; R I Cohen; P Paras; M Gravel; P E Braun; L D Hudson
Journal:  J Neurosci       Date:  1999-01-15       Impact factor: 6.167

6.  Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice.

Authors:  J I Nagy; A-V Ionescu; B D Lynn; J E Rash
Journal:  Glia       Date:  2003-12       Impact factor: 7.452

7.  Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve.

Authors:  Kelly R Monk; Jianqiang Wu; Jon P Williams; Brenda A Finney; Maureen E Fitzgerald; Marie-Dominique Filippi; Nancy Ratner
Journal:  Neuron Glia Biol       Date:  2007-08

8.  Identification of phosphorylated form of 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) as 46 kDa phosphoprotein in brain non-synaptic mitochondria overloaded by calcium.

Authors:  Tamara Azarashvili; Olga Krestinina; Anastasia Galvita; Dmitry Grachev; Yulia Baburina; Rolf Stricker; Georg Reiser
Journal:  J Bioenerg Biomembr       Date:  2014-02-18       Impact factor: 2.945

9.  Expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro.

Authors:  Lijuan Yang; Enci Mary Kan; Jia Lu; Chunyun Wu; Eng-Ang Ling
Journal:  J Neuroinflammation       Date:  2014-08-23       Impact factor: 8.322

Review 10.  The Functions of Mitochondrial 2',3'-Cyclic Nucleotide-3'-Phosphodiesterase and Prospects for Its Future.

Authors:  Krestinina Olga; Baburina Yulia; Papadopoulos Vassilios
Journal:  Int J Mol Sci       Date:  2020-05-01       Impact factor: 5.923
  10 in total

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