Literature DB >> 7931360

n-3 fatty acid deficiency increases brain protein synthesis in the free-moving adult rat.

M Giaume1, N Gay, V Baubet, A Gharib, G Durand, P Bobillier, N Sarda.   

Abstract

The autoradiographic method with L-[35S]methionine was used to determine the effects of an n-3 fatty acid deficiency on brain protein synthesis. Brain protein synthesis was significantly increased (from 50 to 150%) in 45 of the 52 brain structures studied in n-3 fatty acid-deficient rats as compared with control animals. Biochemical analysis confirmed the increase in overall rate of protein synthesis in brain as a whole.

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Year:  1994        PMID: 7931360     DOI: 10.1046/j.1471-4159.1994.63051995.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN: 0022-3042            Impact factor:   5.372


  2 in total

1.  Unusual effects of some vegetable oils on the survival time of stroke-prone spontaneously hypertensive rats.

Authors:  M Z Huang; S Watanabe; T Kobayashi; A Nagatsu; J Sakakibara; H Okuyama
Journal:  Lipids       Date:  1997-07       Impact factor: 1.880

2.  Effect of n-3 fatty acid deficiency on fatty acid composition and metabolism of aminophospholipids in rat brain synaptosomes.

Authors:  A Ikemoto; M Ohishi; N Hata; Y Misawa; Y Fujii; H Okuyama
Journal:  Lipids       Date:  2000-10       Impact factor: 1.880

  2 in total

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