| Literature DB >> 7931235 |
J C Delumeau1, D Bentué-Ferrer, J M Gandon, R Amrein, S Belliard, H Allain.
Abstract
Recent data obtained in animals and in humans suggest that both MAO-A and MAO-B inhibitors present cognitive enhancing properties of possible interest in the treatment of cognitive disorders. In addition, the rational for using selegiline as a neuroprotector in Parkinson's disease may also be applicable in Alzheimer's disease in which a dramatic increase in the MAO-B activity has been reported. It seems then worthwhile to investigate the neuroprotective effect of MAOIs in humans and to assess, furthermore, the real therapeutical benefit of their cognitive enhancing properties.Entities:
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Year: 1994 PMID: 7931235 DOI: 10.1007/978-3-7091-9324-2_34
Source DB: PubMed Journal: J Neural Transm Suppl ISSN: 0303-6995