Literature DB >> 7930776

Experimental animal models of acute pancreatitis.

M M Lerch1, G Adler.   

Abstract

Experimental animal models have been employed to study pancreatitis for more than a century. Although not always related to the disease in humans, they have contributed greatly to our current understanding of the pathophysiology and cell biology of this disease. They have also become a standard tool for testing new and promising treatments against pancreatitis. The following article will review the most commonly used experimental models of pancreatitis and some of the lessons we have learned from them.

Entities:  

Mesh:

Year:  1994        PMID: 7930776

Source DB:  PubMed          Journal:  Int J Pancreatol        ISSN: 0169-4197


  34 in total

Review 1.  Free radicals and the pancreatic acinar cells: role in physiology and pathology.

Authors:  M Chvanov; O H Petersen; A Tepikin
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-12-29       Impact factor: 6.237

2.  Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis.

Authors:  F Polito; A Bitto; N Irrera; F Squadrito; C Fazzari; L Minutoli; D Altavilla
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

3.  Membrane proteome analysis of cerulein-stimulated pancreatic acinar cells: implication for early event of acute pancreatitis.

Authors:  Jangwon Lee; Ji Hye Seo; Joo Weon Lim; Hyeyoung Kim
Journal:  Gut Liver       Date:  2010-03-25       Impact factor: 4.519

4.  Altered gene expression in cerulein-stimulated pancreatic acinar cells: pathologic mechanism of acute pancreatitis.

Authors:  Ji Hoon Yu; Joo Weon Lim; Hyeyoung Kim
Journal:  Korean J Physiol Pharmacol       Date:  2009-12-31       Impact factor: 2.016

5.  Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.

Authors:  W Halangk; M M Lerch; B Brandt-Nedelev; W Roth; M Ruthenbuerger; T Reinheckel; W Domschke; H Lippert; C Peters; J Deussing
Journal:  J Clin Invest       Date:  2000-09       Impact factor: 14.808

6.  Cerulein pancreatitis: oxidative stress, inflammation, and apoptosis.

Authors:  Hyeyoung Kim
Journal:  Gut Liver       Date:  2008-09-30       Impact factor: 4.519

7.  Lycopene inhibits IL-6 expression in cerulein-stimulated pancreatic acinar cells.

Authors:  Miran Kang; Kyung Suk Park; Jeong Yeon Seo; Hyeyoung Kim
Journal:  Genes Nutr       Date:  2010-12-05       Impact factor: 5.523

8.  Inhibitory effect of Patrinia scabiosaefolia on acute pancreatitis.

Authors:  Sang-Wan Seo; Cheung-Seog Park; Seung-Heon Hong; Kang-Beom Kwon; Hyoung-Chul Moon; Bong-Keun Song; Kyung-Yo Kim; Young-Min Park; Ho-Joon Song; Hyung-Min Kim; Sung-Joo Park
Journal:  World J Gastroenterol       Date:  2006-02-21       Impact factor: 5.742

9.  Mechanism of kinin release during experimental acute pancreatitis in rats: evidence for pro- as well as anti-inflammatory roles of oedema formation.

Authors:  Thomas Griesbacher; Irmgard Rainer; Beate Tiran; Edwin Fink; Fred Lembeck; Bernhard A Peskar
Journal:  Br J Pharmacol       Date:  2003-05       Impact factor: 8.739

Review 10.  Autophagy and pancreatitis.

Authors:  Anna S Gukovskaya; Ilya Gukovsky
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2012-09-06       Impact factor: 4.052

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