Literature DB >> 792893

Analgesic evaluation of butorphanol in patients with postoperative wound pain.

R O Bauer, J W Bellville, V Knox, D Capparell.   

Abstract

Two agonist/antagonist analgesics, butorphanol tartrate (test) and pentazocine hydrochloride (standard), were compared in volunteer informed patients experiencing postoperative wound pain. The relative potency (p) is 0.04 (1 mg butorphanol equals 24.3 mg of pentazocine lactate) with upper and lower confidence limits of 0.01 and 0.07 respectively. Butorphanol tartrate in the higher dose appears to have longer duration of effect. The side effects were comparable in the population studied.

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Year:  1976        PMID: 792893

Source DB:  PubMed          Journal:  Proc West Pharmacol Soc        ISSN: 0083-8969


  3 in total

Review 1.  Butorphanol: a review of its pharmacological properties and therapeutic efficacy.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-12       Impact factor: 9.546

2.  The absolute bioavailability of transnasal butorphanol in patients experiencing rhinitis.

Authors:  W C Shyu; K A Pittman; D S Robinson; R H Barbhaiya
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

3.  The effects of age and sex on the systemic availability and pharmacokinetics of transnasal butorphanol.

Authors:  W C Shyu; E A Morgenthien; K A Pittman; R H Barbhaiya
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

  3 in total

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