Literature DB >> 7928677

Glycothiohexide alpha, a novel antibiotic produced by "Sebekia" sp., LL-14E605. III. Structural elucidation.

P T Northcote1, M Siegel, D B Borders, M D Lee.   

Abstract

The chemical structure of a novel thiopeptide antibiotic, glycothiohexide alpha (1), isolated from the fermentation broth of a "Sebekia" species was determined based on extensive 2D NMR studies, as well as, IR, UV, and mass spectral data. The chemical structure of glycothiohexide alpha is closely related to nosiheptide (3) and antibiotic S-54832A.

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Year:  1994        PMID： 7928677     DOI： 10.7164/antibiotics.47.901

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  7 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

Review 2.  Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins.

Authors:  Christopher T Walsh; Michael G Acker; Albert A Bowers
Journal:  J Biol Chem       Date:  2010-06-03       Impact factor: 5.157

Review 3.  Potent Antibiotic Lemonomycin: A Glimpse of Its Discovery, Origin, and Chemical Synthesis.

Authors:  Shunan Tao; Yang Wang; Ran Hong; Sha-Hua Huang
Journal:  Molecules       Date:  2022-07-05       Impact factor: 4.927

4.  Synthetic studies on lemonomycin: construction of the tetracyclic core.

Authors:  Alberto Jiménez-Somarribas; Robert M Williams
Journal:  Tetrahedron       Date:  2013-09-02       Impact factor: 2.457

Review 5.  YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.

Authors:  Brandon J Burkhart; Christopher J Schwalen; Greg Mann; James H Naismith; Douglas A Mitchell
Journal:  Chem Rev       Date:  2017-03-03       Impact factor: 60.622

6.  Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus.

Authors:  Nina M Haste; Wdee Thienphrapa; Dan N Tran; Sandra Loesgen; Peng Sun; Sang-Jip Nam; Paul R Jensen; William Fenical; George Sakoulas; Victor Nizet; Mary E Hensler
Journal:  J Antibiot (Tokyo)       Date:  2012-10-10       Impact factor: 2.649

7.  De Novo Synthesis of an l-Lemonose Thioglycoside Donor from d-Threonine.

Authors:  Eric D Huseman; Steven D Townsend
Journal:  Tetrahedron Lett       Date:  2021-04-22       Impact factor: 2.032
  7 in total

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