Literature DB >> 7924905

Effects of fluorine substitution on drug metabolism: pharmacological and toxicological implications.

B K Park1, N R Kitteringham.   

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Year:  1994        PMID： 7924905     DOI： 10.3109/03602539408998319

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


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  17 in total

1.  From bifunctional to trifunctional (tricomponent nucleophile-transition metal-lewis acid) catalysis: the catalytic, enantioselective α-fluorination of acid chlorides.

Authors:  Jeremy Erb; Daniel H Paull; Travis Dudding; Lee Belding; Thomas Lectka
Journal:  J Am Chem Soc       Date:  2011-04-22       Impact factor: 15.419

2.  Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA.

Authors:  Ariane Wohlfarth; Marisol S Castaneto; Mingshe Zhu; Shaokun Pang; Karl B Scheidweiler; Robert Kronstrand; Marilyn A Huestis
Journal:  AAPS J       Date:  2015-02-28       Impact factor: 4.009

Review 3.  Idiosyncratic drug reactions. Metabolic bioactivation as a pathogenic mechanism.

Authors:  M Pirmohamed; S Madden; B K Park
Journal:  Clin Pharmacokinet       Date:  1996-09       Impact factor: 6.447

Review 4.  Cardiovascular safety of tyrosine kinase inhibitors: with a special focus on cardiac repolarisation (QT interval).

Authors:  Rashmi R Shah; Joel Morganroth; Devron R Shah
Journal:  Drug Saf       Date:  2013-05       Impact factor: 5.606

5.  Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes.

Authors:  Neil Vasdev; Peter N Dorff; James P O'Neil; Frederick T Chin; Stephen Hanrahan; Henry F VanBrocklin
Journal:  Bioorg Med Chem       Date:  2011-03-21       Impact factor: 3.641

Review 6.  The role of radionuclide probes for monitoring anti-tumor drugs efficacy: A brief review.

Authors:  Renata Salgado Fernandes; Carolina de Aguiar Ferreira; Daniel Cristian Ferreira Soares; Anna Margherita Maffione; Danyelle M Townsend; Domenico Rubello; André Luís Branco de Barros
Journal:  Biomed Pharmacother       Date:  2017-09-12       Impact factor: 6.529

7.  Strategies for the Catalytic Enantioselective Synthesis of α-Trifluoromethyl Amines.

Authors:  Chibueze I Onyeagusi; Steven J Malcolmson
Journal:  ACS Catal       Date:  2020-10-12       Impact factor: 13.084

8.  Mechanism of clozapine-induced agranulocytosis : current status of research and implications for drug development.

Authors:  M Pirmohamed; K Park
Journal:  CNS Drugs       Date:  1997-02       Impact factor: 5.749

9.  Synthesis of novel 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole derivatives as antiproliferative agents: a structure-activity relationship study.

Authors:  S B Benaka Prasad; K Vinaya; C S Ananda Kumar; Sanjay Swarup; K S Rangappa
Journal:  Invest New Drugs       Date:  2008-12-06       Impact factor: 3.850

Review 10.  Benzisoxazole: a privileged scaffold for medicinal chemistry.

Authors:  K P Rakesh; C S Shantharam; M B Sridhara; H M Manukumar; Hua-Li Qin
Journal:  Medchemcomm       Date:  2017-10-31       Impact factor: 3.597
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