Literature DB >> 7923832

Calcitonin-producing insulinoma: clinical, immunocytochemical and cytogenetical study.

M J Bugalho1, L Roque, L G Sobrinho, A Hoog, J F Nunes, J M Almeida, C N Leitão, J R Santos, M C Pereira, M A Santos.   

Abstract

The case of a patient with a large goitre associated with hypercalcitoninaemia and fasting hypoglycaemia is reported. Pentagastrin (PG) test was negative. Repeated measurements of fasting glycaemia, insulin and C peptide established the diagnosis of insulinoma. After localization by endoscopic ultrasonography, a distal pancreatectomy was performed and a small insulinoma was recovered. Glycaemia and calcitonin (CT) became normal. The tumour cells displayed a strong immunoreactivity for insulin and CT. Cytogenetical evaluation of the tumour revealed a translocation t(1;9) (p13;p22).

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Year:  1994        PMID： 7923832     DOI： 10.1111/j.1365-2265.1994.tb02539.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  5 in total

Review 1.  Calcitonin-Producing Neuroendocrine Neoplasms of the Pancreas: Clinicopathological Study of 25 Cases and Review of the Literature.

Authors:  Silvia Uccella; Annika Blank; Roberta Maragliano; Fausto Sessa; Aurel Perren; Stefano La Rosa
Journal:  Endocr Pathol       Date:  2017-12       Impact factor: 3.943

2.  Calcitonin Screening in Nodular Thyroid Disease: Is There a Definitive Answer?

Authors:  Catarina Silvestre; Joaquim Sampaio Matias; Helena Proença; Maria João Bugalho
Journal:  Eur Thyroid J       Date:  2018-12-05

3.  Chromosomal imbalances in primary and metastatic pancreatic carcinoma as detected by interphase cytogenetics: basic findings and clinical aspects.

Authors:  N Zojer; M Fiegl; L Müllauer; A Chott; S Roka; J Ackermann; M Raderer; H Kaufmann; A Reiner; H Huber; J Drach
Journal:  Br J Cancer       Date:  1998-04       Impact factor: 7.640

4.  Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms.

Authors:  Sven-Petter Haugvik; Ludmila Gorunova; Lisbeth Haugom; Anne Mette Eibak; Ivar Prydz Gladhaug; Sverre Heim; Francesca Micci
Journal:  Oncol Rep       Date:  2014-07-11       Impact factor: 3.906

5.  Malignant Insulinoma with Multiple Liver Metastases and Hypercalcitoninemia in a Patient with Type 2 Diabetes Mellitus Presenting as Recurrent Episodes of Diaphoresis due to Severe Hypoglycemia.

Authors:  Marco Ciacciarelli; Gianluca Caruso; Marco Rengo; Piero Maceroni; Carmen Misurale; Eleonora D'Armiento; Alessandro Polidoro; Cristina Napoli; Alberto Lombardini; Umberto Ceratti; Ruben Manuel Luciano Colunga Biancatelli; Leonardo Calvosa; Romina Milanese; Sonia Ferri; Teresa Massaro; Andrea Lorusso; Veronica Sorrentino; Vincenzo Petrozza; Luigi Iuliano
Journal:  Case Rep Endocrinol       Date:  2020-01-31
  5 in total

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