Literature DB >> 7923807

Human prostatic acid phosphatase: selected properties and practical applications.

W S Ostrowski1, R Kuciel.   

Abstract

Human prostatic acid phosphatase (EC 3.1.3.2) is a non-specific phosphomonoesterase, synthetized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Gene coding this protein is localized on chromosome 3. Since many years prostatic phosphatase has been used as a marker of diagnosis and therapy control of cancer of the prostate gland. The biological role of this enzyme, however, remains unknown and needs further exploration.

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Year:  1994        PMID： 7923807     DOI： 10.1016/0009-8981(94)90209-7

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  15 in total

1.  Prostate Cancer - Old Problems and New Approaches. (Part II. Diagnostic and Prognostic Markers, Pathology and Biological Aspects).

Authors:  Kenneth V Honn; Amer Aref; Yong Q Chen; Michael L Cher; John D Crissman; Jeffrey D Forman; Xiang Gao; David Grignon; Maha Hussain; Arthur T Porter; Edson J Pontes; Bruce Redman; Wael Sakr; Richard Severson; Dean G Tang; David P Wood
Journal:  Pathol Oncol Res       Date:  1996       Impact factor: 3.201

2.  An 18 kDa acid phosphatase from chicken heart possesses phosphotransferase activity.

Authors:  Rubina Naz; Asma Saeed; Ahmad Saeed
Journal:  Protein J       Date:  2006-02       Impact factor: 2.371

3.  Deceased expression of prostatic acid phosphatase in primary sensory neurons after peripheral nerve injury.

Authors:  Bo Huang; Xia Li; Xiao-Chun Zhu; Yi-Sheng Lu
Journal:  Int J Clin Exp Pathol       Date:  2014-12-01

4.  Concentration-dependent dissociation/association of human prostatic acid phosphatase.

Authors:  Ewa Luchter-Wasylewska; Marcin Wasylewski; Klaus-Heinrich Röhm
Journal:  J Protein Chem       Date:  2003-04

5.  Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine.

Authors:  Mark J Zylka; Nathaniel A Sowa; Bonnie Taylor-Blake; Margaret A Twomey; Annakaisa Herrala; Vootele Voikar; Pirkko Vihko
Journal:  Neuron       Date:  2008-10-09       Impact factor: 17.173

6.  Pain management using photobiomodulation: Mechanisms, location, and repeatability quantified by pain threshold and neural biomarkers in mice.

Authors:  Marcelo Victor Pires de Sousa; Masayoshi Kawakubo; Cleber Ferraresi; Beatriz Kaippert; Elisabeth Mateus Yoshimura; Michael R Hamblin
Journal:  J Biophotonics       Date:  2018-05-18       Impact factor: 3.207

7.  Identification of gp17 glycoprotein and characterization of prostatic acid phosphatase (PAP) and carboxypeptidase E (CPE) fragments in a human seminal plasma fraction interacting with concanavalin A.

Authors:  A C Marquínez; A M Andreetta; N González; C Wolfenstein-Todel; J M Scacciati de Cerezo
Journal:  J Protein Chem       Date:  2003-07

8.  High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.

Authors:  Eric S McCoy; Wendy A Lea; Bryan T Mott; David J Maloney; Ajit Jadhav; Anton Simeonov; Mark J Zylka
Journal:  J Biomol Screen       Date:  2012-11-27

9.  Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception.

Authors:  Nathaniel A Sowa; Kunjumon I Vadakkan; Mark J Zylka
Journal:  PLoS One       Date:  2009-01-22       Impact factor: 3.240

10.  Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats.

Authors:  Bonnie Taylor-Blake; Mark J Zylka
Journal:  PLoS One       Date:  2010-01-13       Impact factor: 3.240
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