| Literature DB >> 7922130 |
J A Farrera1, A Jaumà, J M Ribó, M A Peiré, P P Parellada, S Roques-Choua, E Bienvenue, P Seta.
Abstract
Bilirubin, biliverdin and their serum albumin complexes were tested as oxyradical scavengers (superoxide generated by the xanthine/xanthine oxidase system and peroxyl radical-trapping antioxidant ability). As superoxide scavengers the free bile pigments showed activities near to that of serum albumin, higher than the water soluble vitamin E analog Trolox and lower than ascorbic acid. The peroxyl radical-trapping antioxidant abilities of the tested bile pigments were much higher than those of the serum albumin and of the same order as their serum albumin complexes. This interaction with peroxyl radicals showed different stoichiometric factors for bilirubin (approximately 2) and biliverdin (approximately 4).Entities:
Mesh：
Substances：
Year: 1994 PMID： 7922130 DOI： 10.1016/s0968-0896(00)82013-1
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641