| Literature DB >> 7922125 |
S Fabre1, M Prudhomme, M Sancelme, M Rapp.
Abstract
Structural modifications were carried out on rebeccamycin, an antitumour antibiotic, to obtain analogues. The inhibitory potencies of these analogues against protein kinase C are compared. The method described represents an alternative route to the staurosporine aglycone, a potent protein kinase C inhibitor.Entities:
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Year: 1994 PMID： 7922125 DOI： 10.1016/s0968-0896(00)82003-9
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641