Literature DB >> 7920268

Capacity of a model immune network.

G Weisbuch1, M Oprea.   

Abstract

The capacity of a model immune network in terms of the number of different antigens that can be vaccinated against without any memory lost is computed and tested by numerical simulations. We also investigate memory loss and failure to vaccinate due to overcrowding the network with too many antigens. The computations are done for two different strategies for proliferation, one implying all the antigen specific clones and the second one being more thrifty.

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Year:  1994        PMID： 7920268     DOI： 10.1007/bf02458273

Source DB:  PubMed          Journal:  Bull Math Biol        ISSN： 0092-8240            Impact factor:   1.758


  8 in total

1.  Localized memories in idiotypic networks.

Authors:  G Weisbuch; R J De Boer; A S Perelson
Journal:  J Theor Biol       Date:  1990-10-21       Impact factor: 2.691

2.  Size and connectivity as emergent properties of a developing immune network.

Authors:  R J de Boer; A S Perelson
Journal:  J Theor Biol       Date:  1991-04-07       Impact factor: 2.691

3.  Dynamics and topology of idiotypic networks.

Authors:  A U Neumann; G Weisbuch
Journal:  Bull Math Biol       Date:  1992-09       Impact factor: 1.758

4.  Window automata analysis of population dynamics in the immune system.

Authors:  A U Neumann; G Weisbuch
Journal:  Bull Math Biol       Date:  1992-01       Impact factor: 1.758

Review 5.  Regulatory influences of neonatal multispecific antibodies on the developing B cell repertoire.

Authors:  M Vakil; J F Kearney
Journal:  Int Rev Immunol       Date:  1988-03       Impact factor: 5.311

6.  Unreasonable implications of reasonable idiotypic network assumptions.

Authors:  R J De Boer; P Hogeweg
Journal:  Bull Math Biol       Date:  1989       Impact factor: 1.758

Review 7.  Cellular mechanisms of immunologic tolerance.

Authors:  G J Nossal
Journal:  Annu Rev Immunol       Date:  1983       Impact factor: 28.527

8.  Towards a network theory of the immune system.

Authors:  N K Jerne
Journal:  Ann Immunol (Paris)       Date:  1974-01
  8 in total
  2 in total

1.  Immune networks modeled by replicator equations.

Authors:  P F Stadler; P Schuster; A S Perelson
Journal:  J Math Biol       Date:  1994       Impact factor: 2.259

2.  Memory capacity in large idiotypic networks.

Authors:  J H Boutet de Monvel; O C Martin
Journal:  Bull Math Biol       Date:  1995-01       Impact factor: 1.758
  2 in total

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