| Literature DB >> 7918841 |
U Y Khoo1, D J Newman, W K Miller, C P Price.
Abstract
The peroxidase activity of haemoglobin A was characterized for non-glycated and glycated haemoglobin (HbA1) within the pH range 4.5 to 6.0, by measuring the rate of oxidation of 5-aminosalicylic acid following the degradation of H2O2. Glycation was found to significantly lower the pH activity of haemoglobin peroxidase throughout the pH range. However, in the presence of 100 mmol/l sorbitol the pH activity profile of glycated haemoglobin was significantly elevated whilst that of non-glycated haemoglobin remained unchanged.Entities:
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Year: 1994 PMID： 7918841 DOI： 10.1515/cclm.1994.32.6.435
Source DB: PubMed Journal: Eur J Clin Chem Clin Biochem ISSN： 0939-4974