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Literature DB >> 7917991

Alanine at position 73 of HLA-C is associated with psoriasis vulgaris in Finland.

I Ikäheimo¹, S Silvennoinen-Kassinen, J Karvonen, A Tiilikainen.

Abstract

A close association was found between a specific sequence of HLA-C and psoriasis vulgaris in Finnish patients (chi 2 = 18.4, P = 1.78 x 10(-5)). This sequence codes for alanine at position 73 of the HLA-C molecule in the antigen binding cleft, and alanine may play a role in susceptibility to the disease.

Entities: Chemical Disease Gene Species

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Substances：

Year: 1994 PMID： 7917991 DOI： 10.1111/j.1365-2133.1994.tb08501.x

Source DB: PubMed Journal: Br J Dermatol ISSN： 0007-0963 Impact factor: 9.302

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Cited

7 in total

1. Immunogenetic profile of psoriasis vulgaris: association with haplotypes A2,B13,Cw6,DR7,DQA10201 and A1,B17,Cw6,DR7,DQA10201.

Authors: I Ikaheimo; S Silvennoinen-Kassinen; J Karvonen; T Jarvinen; A Tiilikainen
Journal: Arch Dermatol Res Date: 1996-02 Impact factor: 3.017

2. The complete genomic sequence of 424,015 bp at the centromeric end of the HLA class I region: gene content and polymorphism.

Authors: T Guillaudeux; M Janer; G K Wong; T Spies; D E Geraghty
Journal: Proc Natl Acad Sci U S A Date: 1998-08-04 Impact factor: 11.205

Review 3. HLA-C revisited. Ten years of change.

Authors: C S Falk; D J Schendel
Journal: Immunol Res Date: 1997 Impact factor: 2.829

4. PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis.

Authors: G K Tay; J Hui; S Gaudieri; M Schmitt-Egenolf; O P Martinez; C Leelayuwat; J F Williamson; T H Eiermann; R L Dawkins
Journal: Clin Exp Immunol Date: 2000-03 Impact factor: 4.330

Alanine at position 73 of HLA-C is associated with psoriasis vulgaris in Finland.

1. Immunogenetic profile of psoriasis vulgaris: association with haplotypes A2,B13,Cw6,DR7,DQA10201 and A1,B17,Cw6,DR7,DQA10201.

2. The complete genomic sequence of 424,015 bp at the centromeric end of the HLA class I region: gene content and polymorphism.

Review 3. HLA-C revisited. Ten years of change.

4. PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis.

5. HLA risk haplotype Cw6,DR7,DQA1*0201 and HLA-Cw6 with reference to the clinical picture of psoriasis vulgaris.

6. Evaluation of Psoriasis Genetic Risk Based on Five Susceptibility Markers in a Population from Northern Poland.

7. ERAP1 and HLA-C06* are strongly associated with the risk of psoriasis in the population of northern Poland.

Alanine at position 73 of HLA-C is associated with psoriasis vulgaris in Finland.

1. Immunogenetic profile of psoriasis vulgaris: association with haplotypes A2,B13,Cw6,DR7,DQA1*0201 and A1,B17,Cw6,DR7,DQA1*0201.

2. The complete genomic sequence of 424,015 bp at the centromeric end of the HLA class I region: gene content and polymorphism.

Review 3. HLA-C revisited. Ten years of change.

4. PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis.

5. HLA risk haplotype Cw6,DR7,DQA1*0201 and HLA-Cw6 with reference to the clinical picture of psoriasis vulgaris.

6. Evaluation of Psoriasis Genetic Risk Based on Five Susceptibility Markers in a Population from Northern Poland.

7. ERAP1 and HLA-C*06 are strongly associated with the risk of psoriasis in the population of northern Poland.

1. Immunogenetic profile of psoriasis vulgaris: association with haplotypes A2,B13,Cw6,DR7,DQA10201 and A1,B17,Cw6,DR7,DQA10201.

7. ERAP1 and HLA-C06* are strongly associated with the risk of psoriasis in the population of northern Poland.