| Literature DB >> 7917330 |
Abstract
One parental copy of an imprinted gene is invariably expressed during development. The characteristic of the heritable epigenetic germline imprint remains elusive, but recent evidence stresses the necessity for additional post-zygotic epigenetic modifications to account for this temporal and tissue-specific mono-allelic expression. Preliminary insight into a diversity of post-zygotic control mechanisms is beginning to emerge.Mesh:
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Year: 1994 PMID: 7917330 DOI: 10.1016/0955-0674(94)90031-0
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382