Literature DB >> 7916948

The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases.

S D Miller1, W J Karpus.   

Abstract

A variety of experimental approaches are currently being evaluated for controlling CD4+ T helper 1 (Th1)-mediated autoimmune pathology. Here, Stephen Miller and William Karpus compare and contrast the efficacies of various antigen-specific regulatory strategies. Particular emphasis is placed on the mechanisms of peripheral immune tolerance and how this may be used in the treatment and analysis of the pathologic T-cell repertoire in autoimmune and virus-induced demyelinating diseases.

Entities:  

Mesh：

Year:  1994        PMID： 7916948     DOI： 10.1016/0167-5699(94)90173-2

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  47 in total

1.  Prevalent class I-restricted T-cell response to the Theiler's virus epitope Db:VP2121-130 in the absence of endogenous CD4 help, tumor necrosis factor alpha, gamma interferon, perforin, or costimulation through CD28.

Authors:  A J Johnson; M K Njenga; M J Hansen; S T Kuhns; L Chen; M Rodriguez; L R Pease
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

Review 2.  Regulation of experimental autoimmune encephalomyelitis by chemokines and chemokine receptors.

Authors:  Adam Elhofy; Kevin J Kennedy; Brian T Fife; William J Karpus
Journal:  Immunol Res       Date:  2002       Impact factor: 2.829

3.  Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis.

Authors:  Junda Kel; Judith Oldenampsen; Mariken Luca; Jan Wouter Drijfhout; Frits Koning; Lex Nagelkerken
Journal:  Am J Pathol       Date:  2007-01       Impact factor: 4.307

4.  Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Authors:  William J Karpus; Kevin J Kennedy; Brian T Fife; Jamie L Bennett; Mauro C Dal Canto; Steven L Kunkel; Nicholas W Lukacs
Journal:  J Neurovirol       Date:  2006-08       Impact factor: 2.643

Review 5.  Cytokine-induced inflammation in the central nervous system revisited.

Authors:  J A Martiney; C Cuff; M Litwak; J Berman; C F Brosnan
Journal:  Neurochem Res       Date:  1998-03       Impact factor: 3.996

6.  Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.

Authors:  M T Lin; S A Stohlman; D R Hinton
Journal:  J Virol       Date:  1997-01       Impact factor: 5.103

7.  Loss of Allograft Inflammatory Factor-1 Ameliorates Experimental Autoimmune Encephalomyelitis by Limiting Encephalitogenic CD4 T-Cell Expansion.

Authors:  Prameladevi Chinnasamy; Sarah E Lutz; Dario F Riascos-Bernal; Venkatesh Jeganathan; Isabel Casimiro; Celia F Brosnan; Nicholas E S Sibinga
Journal:  Mol Med       Date:  2015-01-06       Impact factor: 6.354

8.  Mouse models of multiple sclerosis: experimental autoimmune encephalomyelitis and Theiler's virus-induced demyelinating disease.

Authors:  Derrick P McCarthy; Maureen H Richards; Stephen D Miller
Journal:  Methods Mol Biol       Date:  2012

9.  A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination.

Authors:  T E Lane; M T Liu; B P Chen; V C Asensio; R M Samawi; A D Paoletti; I L Campbell; S L Kunkel; H S Fox; M J Buchmeier
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

10.  Prevention and treatment of experimental autoimmune encephalomyelitis with clonotypic CDR3 peptides: CD4(+) Foxp3(+) T-regulatory cells suppress interleukin-2-dependent expansion of myelin basic protein-specific T cells.

Authors:  Abigail C Buenafe; Shayne Andrew; Michael Afentoulis; Halina Offner; Arthur A Vandenbark
Journal:  Immunology       Date:  2010-01-06       Impact factor: 7.397
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