Literature DB >> 7916755

[Quantification of DNA using image analysis on paraffin sections].

M Lorenzato1, A Lallemand, B Visseaux-Coletto, D Gaillard.   

Abstract

With the new softwares that are available, it is now possible to measure the cellular DNA content on Feulgen stained paraffin sections, without enzymatic dissociation of the samples. The main advantage of this technique is to preserve the cellular histological context and to select the right cells that have to be analyzed. The application is of course to obtain information about cancer prognosis, but it can also be very useful in non tumoral pathology. The DNA measurement on paraffin sections can be applied to the diagnosis of triploidy or tetraploïdy in spontaneous abortions without any karyotype.

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Year:  1994        PMID: 7916755

Source DB:  PubMed          Journal:  Ann Pathol        ISSN: 0242-6498            Impact factor:   0.407


  1 in total

1.  Oncogenic human papillomaviruses and ploidy in cervical lesions.

Authors:  S Rihet; M Lorenzato; C Clavel
Journal:  J Clin Pathol       Date:  1996-11       Impact factor: 3.411

  1 in total

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