Literature DB >> 7916708

Isolation of rat cDNA clones coding for the autoantigen SS-B/La: detection of species-specific variations.

I Semsei1, H Tröster, H Bartsch, M Schwemmle, G L Igloi, M Bachmann.   

Abstract

Clones of cDNA coding for the autoantigen La (or SS-B) were isolated from a library made from rat liver. A comparison of the rat La cDNA (encoding from nt 38 to 1281 for rat La protein) with the sequences known for human and bovine La protein resulted in the identification of species-specific inserts. The inserts seem to be the result of multiplication of flanking sequences during evolution. In addition to these variations, we observed that rat La cDNAs exhibit non-canonical polyadenylation sites. Finally, a databank search resulted in the identification of a DNA sequence originally termed as TAG or TSG20X (GenBank accession No. X61893) which represents the C terminus of mouse La/SS-B protein.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 7916708     DOI： 10.1016/0378-1119(93)90378-g

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  13 in total

1.  Key residues revealed in a major conformational epitope of the U1-70K protein.

Authors:  E Welin Henriksson; M Wahren-Herlenius; I Lundberg; E Mellquist; I Pettersson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

2.  Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.

Authors:  Erna A van Niekerk; Dianna E Willis; Jay H Chang; Kerstin Reumann; Tilman Heise; Jeffery L Twiss
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-23       Impact factor: 11.205

Review 3.  Structure and function of La and Ro RNPs.

Authors:  W J van Venrooij; R L Slobbe; G J Pruijn
Journal:  Mol Biol Rep       Date:  1993-08       Impact factor: 2.316

4.  Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme.

Authors:  P Hühn; G J Pruijn; W J van Venrooij; M Bachmann
Journal:  Nucleic Acids Res       Date:  1997-01-15       Impact factor: 16.971

5.  The nuclear autoantigen La/SS-associated antigen B: one gene, three functional mRNAs.

Authors:  D Grölz; M Bachmann
Journal:  Biochem J       Date:  1997-04-01       Impact factor: 3.857

6.  Developmental characterization of a Drosophila RNA-binding protein homologous to the human systemic lupus erythematosus-associated La/SS-B autoantigen.

Authors:  C Bai; Z Li; P P Tolias
Journal:  Mol Cell Biol       Date:  1994-08       Impact factor: 4.272

7.  The human autoantigen La/SS-B accelerates herpes simplex virus type 1 replication in transfected mouse 3T3 cells.

Authors:  M Bachmann; H Deister; A Pautz; J Laubinger; M Schmitz; D Falke; J Podlech; D Grölz
Journal:  Clin Exp Immunol       Date:  1998-06       Impact factor: 4.330

8.  Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytes.

Authors:  F H Simons; G J Pruijn; W J van Venrooij
Journal:  J Cell Biol       Date:  1994-06       Impact factor: 10.539

9.  Nuclear import and the evolution of a multifunctional RNA-binding protein.

Authors:  J S Rosenblum; L F Pemberton; N Bonifaci; G Blobel
Journal:  J Cell Biol       Date:  1998-11-16       Impact factor: 10.539

10.  Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts.

Authors:  M Cartellieri; A Feldmann; S Koristka; C Arndt; S Loff; A Ehninger; M von Bonin; E P Bejestani; G Ehninger; M P Bachmann
Journal:  Blood Cancer J       Date:  2016-08-12       Impact factor: 11.037
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.