Literature DB >> 7916658

The fission yeast cdc18+ gene product couples S phase to START and mitosis.

T J Kelly1, G S Martin, S L Forsburg, R J Stephen, A Russo, P Nurse.   

Abstract

Commitment to the cell cycle in fission yeast requires the function of the cdc10+ transcriptional activator at START. The product of the cdc18+ gene is a major downstream target of cdc10+, and transcription of cdc18+ is activated by cdc10+ during passage through START. The cdc18+ function is required for entry into S phase. In addition, the product of the cdc18+ gene is part of the checkpoint control that prevents mitosis from occurring until S phase is completed. Thus, cdc18+ plays a key role in coupling S phase to START and mitosis.

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Year:  1993        PMID： 7916658     DOI： 10.1016/0092-8674(93)90427-r

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  203 in total

1.  Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints.

Authors:  M Shimada; D Okuzaki; S Tanaka; T Tougan; K K Tamai; C Shimoda; H Nojima
Journal:  Mol Biol Cell       Date:  1999-12       Impact factor: 4.138

2.  Association of fission yeast Orp1 and Mcm6 proteins with chromosomal replication origins.

Authors:  Y Ogawa; T Takahashi; H Masukata
Journal:  Mol Cell Biol       Date:  1999-10       Impact factor: 4.272

3.  A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage.

Authors:  T Takeda; K Ogino; E Matsui; M K Cho; H Kumagai; T Miyake; K Arai; H Masai
Journal:  Mol Cell Biol       Date:  1999-08       Impact factor: 4.272

4.  Analysis of mid1p, a protein required for placement of the cell division site, reveals a link between the nucleus and the cell surface in fission yeast.

Authors:  A Paoletti; F Chang
Journal:  Mol Biol Cell       Date:  2000-08       Impact factor: 4.138

5.  Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication.

Authors:  S K Yanow; Z Lygerou; P Nurse
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

6.  MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint.

Authors:  K Labib; S E Kearsey; J F Diffley
Journal:  Mol Biol Cell       Date:  2001-11       Impact factor: 4.138

7.  The role of nucleotide binding and hydrolysis in the function of the fission yeast cdc18(+) gene product.

Authors:  D DeRyckere; C L Smith; G S Martin
Journal:  Genetics       Date:  1999-04       Impact factor: 4.562

8.  Plo1(+) regulates gene transcription at the M-G(1) interval during the fission yeast mitotic cell cycle.

Authors:  Mark Anderson; Szu Shien Ng; Vanessa Marchesi; Fiona H MacIver; Frances E Stevens; Tracy Riddell; David M Glover; Iain M Hagan; Christopher J McInerny
Journal:  EMBO J       Date:  2002-11-01       Impact factor: 11.598

9.  Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.

Authors:  T Takeda; K Ogino; K Tatebayashi; H Ikeda; H Masai
Journal:  Mol Biol Cell       Date:  2001-05       Impact factor: 4.138

10.  Size and Structure of Replicating Mitochondrial DNA in Cultured Tobacco Cells.

Authors:  D. J. Oldenburg; A. J. Bendich
Journal:  Plant Cell       Date:  1996-03       Impact factor: 11.277
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