Literature DB >> 7914866

Characterization of a yeast artificial chromosome from human chromosome band 13q12 containing the FLT1 and FLT3 receptor-type tyrosine kinase genes.

A Imbert1, O Rosnet, S Marchetto, V Ollendorff, D Birnbaum, M J Pébusque.   

Abstract

A yeast artificial chromosome containing the two receptor-type tyrosine kinase genes FLT1 and FLT3 was isolated, analyzed, and compared to a genomic map in order to establish their organization and linkage. FLT1 and FLT3 are physically linked in a head-to-tail configuration and separated by about 150 kb. The region contains three CpG islands. Two of them are likely to correspond to FLT1 and FLT3, whereas the third one is suggestive of another putative, unidentified RTK gene.

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Year:  1994        PMID: 7914866     DOI: 10.1159/000133817

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  2 in total

1.  Genomic organization of the extracellular coding region of the human FGFR4 and FLT4 genes: evolution of the genes encoding receptor tyrosine kinases with immunoglobulin-like domains.

Authors:  F Agnès; M M Toux; C André; F Galibert
Journal:  J Mol Evol       Date:  1997-07       Impact factor: 2.395

2.  Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

Authors:  J Lee; A Gray; J Yuan; S M Luoh; H Avraham; W I Wood
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

  2 in total

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