Literature DB >> 7913504

Sulfasalazine induced lupus in rheumatoid arthritis.

M Caulier1, C Dromer, V Andrieu, P Le Guennec, B Fournie.   

Abstract

We describe 2 cases of a lupus syndrome induced by sulfasalazine in rheumatoid arthritis. All symptoms resolved and antihistone antibodies disappeared when sulfasalazine was discontinued. In one patient, perinuclear antineutrophil cytoplasmic antibodies with specificity for myeloperoxidase were found critically increased just before the occurrence of vasculitis.

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Year:  1994        PMID: 7913504

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  3 in total

1.  Does sulphasalazine cause drug induced systemic lupus erythematosus? No effect evident in a prospective randomised trial of 200 rheumatoid patients treated with sulphasalazine or auranofin over five years.

Authors:  M M Gordon; D R Porter; H A Capell
Journal:  Ann Rheum Dis       Date:  1999-05       Impact factor: 19.103

2.  Sulphasalazine-induced systemic lupus erythematous in a patient with ankylosing spondylitis.

Authors:  W C Tsai; C J Chen; J H Yen; H W Liu
Journal:  Clin Rheumatol       Date:  2002-08       Impact factor: 2.980

Review 3.  Sulfasalazine. A review of its pharmacological properties and therapeutic efficacy in the treatment of rheumatoid arthritis.

Authors:  C P Rains; S Noble; D Faulds
Journal:  Drugs       Date:  1995-07       Impact factor: 9.546

  3 in total

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