Literature DB >> 7912307

Lobar pneumonia: an occupational disease in welders.

D Coggon1, H Inskip, P Winter, B Pannett.   

Abstract

We have used data from three analyses of occupational mortality for England and Wales to investigate a suspected hazard of pneumonia in welders. Mortality from the disease was consistently raised in welders aged 15-64, with standardised mortality ratios of 184 (95% CI 150-224) in 1959-63 and 157 (121-200) in 1970-72. Analysis of data for 1979-80 and 1982-90 showed that the increased risk is attributable mainly to an excess of pneumococcal and unspecified lobar pneumonia (proportional mortality ratio 255, 95% CI 192-332). No excess occurred in men above retirement age (65). A possible explanation of these findings is that welding fume reversibly increases the susceptibility of the lung to pneumonic infection. The observation of a similar mortality pattern in moulders and coremakers points to the metallic component of the fume as a possible culprit, but ozone or oxides of nitrogen could also be implicated. There are grounds for lobar pneumonia to be considered an occupational disease in welders.

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Year:  1994        PMID: 7912307     DOI: 10.1016/s0140-6736(94)91056-1

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  29 in total

Review 1.  Immunotoxicology of arc welding fume: worker and experimental animal studies.

Authors:  Patti C Zeidler-Erdely; Aaron Erdely; James M Antonini
Journal:  J Immunotoxicol       Date:  2012-06-26       Impact factor: 3.000

Review 2.  Does occupational exposure to iron promote infection?

Authors:  K Palmer; D Coggon
Journal:  Occup Environ Med       Date:  1997-08       Impact factor: 4.402

3.  Are welders more at risk of respiratory infections?

Authors:  David Coggon; Keith T Palmer
Journal:  Thorax       Date:  2016-04-21       Impact factor: 9.139

4.  A proteome-wide assessment of the oxidative stress paradigm for metal and metal-oxide nanomaterials in human macrophages.

Authors:  Tong Zhang; Matthew J Gaffrey; Dennis G Thomas; Thomas J Weber; Becky M Hess; Karl K Weitz; Paul D Piehowski; Vladislav A Petyuk; Ronald J Moore; Wei-Jun Qian; Brian D Thrall
Journal:  NanoImpact       Date:  2019-11-23

5.  An assessment of the level of awareness and reported complaints regarding occupational health hazards and the utilization of personal protective equipments among the welders of Lahore, Pakistan.

Authors:  Syed Moin Hassan; Usama Nasir; Kanwal Anwar; Usama Talib
Journal:  Int J Occup Environ Health       Date:  2018-01-17

6.  Work-related mortality in England and Wales, 1979-2000.

Authors:  David Coggon; E Clare Harris; Terry Brown; Simon Rice; Keith T Palmer
Journal:  Occup Environ Med       Date:  2010-06-23       Impact factor: 4.402

7.  Inhalation of iron-abundant gas metal arc welding-mild steel fume promotes lung tumors in mice.

Authors:  L M Falcone; A Erdely; V Kodali; R Salmen; L A Battelli; T Dodd; W McKinney; S Stone; M Donlin; H D Leonard; J L Cumpston; J B Cumpston; R N Andrews; M L Kashon; J M Antonini; P C Zeidler-Erdely
Journal:  Toxicology       Date:  2018-07-25       Impact factor: 4.221

8.  Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genes.

Authors:  Alex R Hoffmaster; Karen K Hill; Jay E Gee; Chung K Marston; Barun K De; Tanja Popovic; David Sue; Patricia P Wilkins; Swati B Avashia; Rahsaan Drumgoole; Charles H Helma; Lawrence O Ticknor; Richard T Okinaka; Paul J Jackson
Journal:  J Clin Microbiol       Date:  2006-09       Impact factor: 5.948

9.  Mortality from infectious pneumonia in metal workers: a comparison with deaths from asthma in occupations exposed to respiratory sensitisers.

Authors:  K T Palmer; P Cullinan; S Rice; T Brown; D Coggon
Journal:  Thorax       Date:  2009-08-23       Impact factor: 9.139

10.  Vaccinating welders against pneumonia.

Authors:  Keith T Palmer; Martin Cosgrove
Journal:  Occup Environ Med       Date:  2012-08-23       Impact factor: 4.402

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