Literature DB >> 7912080

Thymocyte lineage commitment: is it instructed or stochastic?

C B Davis1, D R Littman.   

Abstract

Thymocytes co-expressing the CD4 and CD8 co-receptors differentiate into mature T cells that express either CD4 or CD8 and have helper or cytotoxic functions, respectively. Recent studies indicate that commitment to the CD4+ or CD8+ lineages occurs stochastically, but retention of the appropriate co-receptor is required to complete development.

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Year:  1994        PMID： 7912080     DOI： 10.1016/0952-7915(94)90100-7

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  4 in total

Review 1.  Bone Morphogenetic Protein Signaling Regulates Development and Activation of CD4(+) T Cells.

Authors:  Michal Kuczma; Piotr Kraj
Journal:  Vitam Horm       Date:  2015-06-27       Impact factor: 3.421

2.  A genome-wide detection of copy number variations using SNP genotyping arrays in swine.

Authors:  Jiying Wang; Jicai Jiang; Weixuan Fu; Li Jiang; Xiangdong Ding; Jian-Feng Liu; Qin Zhang
Journal:  BMC Genomics       Date:  2012-06-22       Impact factor: 3.969

Review 3.  Transcriptional control of CD4 and CD8 coreceptor expression during T cell development.

Authors:  Wilfried Ellmeier; Lena Haust; Roland Tschismarov
Journal:  Cell Mol Life Sci       Date:  2013-06-21       Impact factor: 9.261

4.  Correlation analyses of CpG island methylation of cluster of differentiation 4 protein with gene expression and T lymphocyte subpopulation traits.

Authors:  Xueyan Zhao; Yanping Wang; Jianfeng Guo; Jiying Wang
Journal:  Asian-Australas J Anim Sci       Date:  2018-03-02       Impact factor: 2.509
  4 in total

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