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Literature DB >> 791111

In vitro comparison of gentamicin, tobramycin, sisomicin, and netilmicin.

Abstract

The antimicrobial activity of gentamicin, tobramycin, sisomicin, and netilmicin (Sch 20569) was compared against 150 strains of organisms. Netilmicin was shown to be the least effective against Pseudomonas strains but to have slightly better activity against Staphylococcus aureus and Escherichia coli than the other agents. The effect of calcium and magnesium in enhancing the differences in activity of these aminoglycosides against Pseudomonas strains was also demonstrated.

Entities: Chemical Species

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Year: 1976 PMID： 791111 PMCID： PMC429827 DOI： 10.1128/AAC.10.4.768

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

5 in total

1. Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin.

Authors: J A Waitz; E L Moss; C G Drube; M J Weinstein
Journal: Antimicrob Agents Chemother Date: 1972-12 Impact factor: 5.191

2. Comparative activity of tobramycin and gentamicin against Pseudomonas, Proteus and Providencia species.

Authors: I B Ducan; J L Penner
Journal: Can Med Assoc J Date: 1975-07-12 Impact factor: 8.262

3. Effect of medium composition on the apparent sensitivity of Pseudomonas aeruginosa to gentamicin.

Authors: L P Garrod; P M Waterworth
Journal: J Clin Pathol Date: 1969-09 Impact factor: 3.411

4. Sisomicin: evaluation in vitro and comparison with gentamicin and tobramycin.

Authors: C C Crowe; E Sanders
Journal: Antimicrob Agents Chemother Date: 1973-01 Impact factor: 5.191

5. In vitro evaluation of a new aminoglycoside derivative of kanamycin, a comparison with tobramycin and gentamycin.

Authors: K Ries; M E Levison; D Kaye
Journal: Antimicrob Agents Chemother Date: 1973-04 Impact factor: 5.191

5 in total

3 in total

In vitro comparison of gentamicin, tobramycin, sisomicin, and netilmicin.

1. Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin.

2. Comparative activity of tobramycin and gentamicin against Pseudomonas, Proteus and Providencia species.

3. Effect of medium composition on the apparent sensitivity of Pseudomonas aeruginosa to gentamicin.

4. Sisomicin: evaluation in vitro and comparison with gentamicin and tobramycin.

5. In vitro evaluation of a new aminoglycoside derivative of kanamycin, a comparison with tobramycin and gentamycin.

1. Correlation of netilmicin agar dilution and disk diffusion susceptibilities.

2. Comparison of netilmicin with gentamicin in the therapy of experimental Escherichia coli meningitis.

3. Netilmicin: clinical efficacy, tolerance, and toxicity.