Literature DB >> 791110

Correlation of resistance to proflavine and penicillin in Escherichia coli.

R C McKellar, C N McKenzie, K J Kushner.   

Abstract

A number of proflavine (PF)-resistant mutants of Escherichia coli B were also resistant to penicillin and cephalothin. Mutants resistant to 1.0 mM PF were 10 times more penicillin resistant than were the PF-susceptible, wild-type cells. Single-step mutants selected for resistance to either PF or penicillin were also resistant to the other drug. None of the resistant mutants tested possessed beta-lactamase activity. These results suggest that resistance to PF and penicillin in E. coli B may be due to permeability changes in the cell envelope.

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Year:  1976        PMID： 791110      PMCID： PMC429826          DOI： 10.1128/AAC.10.4.765

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  ACRIFLAVINE RESISTANCE: A BACTERIOPHAGE MUTATION AFFECTING THE UPTAKE OF DYE BY THE INFECTED BACTERIAL CELLS.

Authors:  S SILVER
Journal:  Proc Natl Acad Sci U S A       Date:  1965-01       Impact factor: 11.205

Review 2.  The beta-lactamases of gram-negative bacteria and their possible physiological role.

Authors:  M H Richmond; R B Sykes
Journal:  Adv Microb Physiol       Date:  1973       Impact factor: 3.517

3.  Proflavin mutagenesis of bacteria.

Authors:  T Kohno; J R Roth
Journal:  J Mol Biol       Date:  1974-10-15       Impact factor: 5.469

4.  Multiple antibiotic resistance due to a single mutation in Neisseria gonorrhoeae.

Authors:  M J Maness; P F Sparling
Journal:  J Infect Dis       Date:  1973-09       Impact factor: 5.226

5.  Mechanisms of drug resistance. The beta-lactamases of gram-negative bacteria including pseudomonads.

Authors:  M H Richmond; G W Jack; R B Sykes
Journal:  Ann N Y Acad Sci       Date:  1971-06-11       Impact factor: 5.691

6.  Resistance of Escherichia coli to penicillins. 8. Physiology of a class II ampicillin-resistant mutant.

Authors:  K Nordström; L G Burman; K G Eriksson-Grennberg
Journal:  J Bacteriol       Date:  1970-03       Impact factor: 3.490

7.  Effects of energy metabolism on the release of bound proflavine from sensitive and resistant Escherichia coli.

Authors:  B M Mehta; M J Gravelle; D J Kushner
Journal:  Antimicrob Agents Chemother       Date:  1973-09       Impact factor: 5.191

8.  Genetic determination of resistance to acriflavine, phenethyl alcohol, and sodium dodecyl sulfate in Escherichia coli.

Authors:  H Nakamura
Journal:  J Bacteriol       Date:  1968-10       Impact factor: 3.490

9.  Ampicillin-resistant mutants of Escherichia coli K-12 with lipopolysaccharide alterations affecting mating ability and susceptibility to sex-specific bacteriophages.

Authors:  D A Monner; S Jonsson; H G Boman
Journal:  J Bacteriol       Date:  1971-08       Impact factor: 3.490

10.  Action of ethylenediaminetetra-acetic acid (EDTA) on carbenicillin-resistant strains of Pseudomonas aeruginosa.

Authors:  E Barrett; A W Asscher
Journal:  J Med Microbiol       Date:  1972-08       Impact factor: 2.472
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  1 in total

1.  Acriflavine-resistant mutant of Streptococcus cremoris.

Authors:  R P Sinha
Journal:  Antimicrob Agents Chemother       Date:  1977-09       Impact factor: 5.191
  1 in total

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