Literature DB >> 7910179

In-hospital evaluation of orthophthalaldehyde as a high level disinfectant for flexible endoscopes.

M J Alfa1, D L Sitter.   

Abstract

One hundred endoscopes used for bronchoscopy (30), gastroscopy (35) or colonoscopy (35) were studied to determine the efficiency of a new high level disinfectant, orthophthalaldehyde (OPA). Manual cleaning was the method studied since this would be the least effective and thereby provide the greatest challenge to the 0.5% (w/v) OPA solution. The OPA was convenient and easy to use since it did not have irritating vapours and as it is used directly, does not require dilution. Our study demonstrated that the OPA was stable for up to 14 days despite repeated re-use. The cleaning/disinfection procedure could achieve a > or = 5 LOG10 reduction in bacterial load. This in-hospital evaluation supports the conclusion that OPA is an effective choice as a high level disinfectant for flexible endoscopes.

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Year:  1994        PMID： 7910179      PMCID： PMC7124318          DOI： 10.1016/0195-6701(94)90075-2

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN： 0195-6701            Impact factor:   3.926


  21 in total

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Journal:  Endoscopy       Date:  1990-07       Impact factor: 10.093

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  10 in total

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Authors:  Georg O Spaun; Trudie A Goers; Richard A Pierce; Maria A Cassera; Sandy Scovil; Lee L Swanstrom
Journal:  Surg Endosc       Date:  2009-12-24       Impact factor: 4.584

Review 2.  Is peracetic acid suitable for the cleaning step of reprocessing flexible endoscopes?

Authors:  Günter Kampf; Patricia M Fliss; Heike Martiny
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3.  Prospective comparative study between the effect of CIDEX® OPA and STERRAD NX on the durability of digital flexible ureteroscope.

Authors:  Saeed H Al Qahtani; Mohamed H Abdelhamied; Abdulrahman H AlMuhrij; Mizyad Y Al Rawashada; Ahmed M Al Askar; Amr M Abdelhamid; Tarek K Fath El-Bab; Ehab M Galal; Mahmoud S Eladawy
Journal:  World J Urol       Date:  2019-05-13       Impact factor: 4.226

4.  Noninvasive ventilation for patients near the end of life: what do we know and what do we need to know?

Authors:  William J Ehlenbach; J Randall Curtis
Journal:  Crit Care Med       Date:  2008-03       Impact factor: 7.598

Review 5.  Antiseptics and disinfectants: activity, action, and resistance.

Authors:  G McDonnell; A D Russell
Journal:  Clin Microbiol Rev       Date:  1999-01       Impact factor: 26.132

Review 6.  New disinfection and sterilization methods.

Authors:  W A Rutala; D J Weber
Journal:  Emerg Infect Dis       Date:  2001 Mar-Apr       Impact factor: 6.883

7.  Residual bioburden in reprocessed side-view endoscopes used for endoscopic retrograde cholangiopancreatography (ERCP).

Authors:  D L N L Ubhayawardana; J Kottahachchi; M M Weerasekera; I W M P Wanigasooriya; S S N Fernando; M De Silva
Journal:  Endosc Int Open       Date:  2013-12

Review 8.  Current and emergent strategies for disinfection of hospital environments.

Authors:  Ana C Abreu; Rafaela R Tavares; Anabela Borges; Filipe Mergulhão; Manuel Simões
Journal:  J Antimicrob Chemother       Date:  2013-07-18       Impact factor: 5.790

9.  A review of current disinfectants for gastrointestinal endoscopic reprocessing.

Authors:  Sanghoon Park; Jae Young Jang; Ja Seol Koo; Jeong Bae Park; Yun Jeong Lim; Su Jin Hong; Sang-Woo Kim; Hoon Jai Chun
Journal:  Clin Endosc       Date:  2013-07-31

10.  An exception to the rule "no association between antibiotic resistance and decreased disinfectant microbicidal efficacy": Orthophthalaldehyde (OPA) and Pseudomonas aeruginosa isolated from ICU and paraplegic patients.

Authors:  R Herruzo; M J Vizcaíno; I Herruzo
Journal:  J Prev Med Hyg       Date:  2017-03
  10 in total

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