Literature DB >> 7908626

6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes.

G N Kumar1, J E Oatis, K R Thornburg, F J Heldrich, E S Hazard, T Walle.   

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Year:  1994        PMID： 7908626

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN： 0090-9556            Impact factor:   3.922


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  6 in total

Review 1.  Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.

Authors:  Maarten J Deenen; Annemieke Cats; Jos H Beijnen; Jan H M Schellens
Journal:  Oncologist       Date:  2011-05-31

2.  Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.

Authors:  C A Jamis-Dow; R W Klecker; A G Katki; J M Collins
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

3.  Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6 alpha-hydroxytaxol.

Authors:  G Kumar; S Ray; T Walle; Y Huang; M Willingham; S Self; K Bhalla
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

4.  Extensive and saturable accumulation of paclitaxel by the human platelet.

Authors:  M D Wild; U K Walle; T Walle
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

Review 5.  Paclitaxel. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer.

Authors:  C M Spencer; D Faulds
Journal:  Drugs       Date:  1994-11       Impact factor: 9.546

6.  Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces.

Authors:  A Sparreboom; M T Huizing; J J Boesen; W J Nooijen; O van Tellingen; J H Beijnen
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333
  6 in total

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