Literature DB >> 7908360

Small virus-like structure in fractions from scrapie hamster brain.

M Ozel1, H Diringer.   

Abstract

The scrapie model in hamsters has been used to search for the agents that cause Creutzfeldt-Jakob disease in man and similar transmissible encephalopathies in animals. We found structures that are extraordinarily small for a virus, but exhibit viral structural properties in negatively stained samples, by electron microscopy in fractions containing scrapie-associated fibrils.

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Mesh：

Year:  1994        PMID： 7908360     DOI： 10.1016/s0140-6736(94)90010-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  6 in total

1.  Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.

Authors:  D Riesner; K Kellings; K Post; H Wille; H Serban; D Groth; M A Baldwin; S B Prusiner
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

Review 2.  Prions, beta-sheets and transmissible dementias: is there still something missing?

Authors:  P P Liberski
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

Review 3.  Is Creutzfeldt-Jakob disease transmitted in blood?

Authors:  M N Ricketts; N R Cashman; E E Stratton; S ElSaadany
Journal:  Emerg Infect Dis       Date:  1997 Apr-Jun       Impact factor: 6.883

4.  Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.

Authors:  K K Hsiao; D Groth; M Scott; S L Yang; H Serban; D Rapp; D Foster; M Torchia; S J Dearmond; S B Prusiner
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-13       Impact factor: 11.205

5.  'Prion' diseases.

Authors:  H C Grant
Journal:  J R Coll Physicians Lond       Date:  1994 Jul-Aug

Review 6.  Prions and related neurological diseases.

Authors:  M Pocchiari
Journal:  Mol Aspects Med       Date:  1994
  6 in total

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