Literature DB >> 7907942

Frequent loss of heterozygosity in the region including BRCA1 on chromosome 17q in squamous cell carcinomas of the esophagus.

T Mori1, T Aoki, T Matsubara, F Iida, X Du, T Nishihira, S Mori, Y Nakamura.   

Abstract

Ninety-four esophageal squamous cell carcinomas were examined for loss of heterozygosity at several loci on the long arm of chromosome 17 (17q), using restriction fragment length polymorphism markers. Loss of heterozygosity was observed in 56 (62%) of 91 tumors that were informative with at least one marker. Comparison of these results with clinicopathological data indicated that the losses on chromosome 17q had occurred at an early stage of carcinogenesis. Detailed deletion mapping in these tumors revealed that the region commonly deleted was within the segment between loci defined by two markers at chromosomal band 17q21.3.

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Year:  1994        PMID： 7907942

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  11 in total

1.  Microsatellite instability and loss of heterozygosity in human pterygia.

Authors:  D A Spandidos; G Sourvinos; H Kiaris; J Tsamparlakis
Journal:  Br J Ophthalmol       Date:  1997-06       Impact factor: 4.638

2.  Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis.

Authors:  Cheryl Marietta; Larry H Thompson; Jane E Lamerdin; P J Brooks
Journal:  Mutat Res       Date:  2009-04-05       Impact factor: 2.433

3.  Genetic instability of BRCA1 gene at locus D17S855 is related to clinicopathological behaviors of gastric cancer from Chinese population.

Authors:  Xue-Rong Chen; Wei-Zhong Zhang; Xing-Qiu Lin; Jin-Wei Wang
Journal:  World J Gastroenterol       Date:  2006-07-14       Impact factor: 5.742

Review 4.  Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: molecular mechanisms of carcinogenesis.

Authors:  Yasushi Toh; Eiji Oki; Kippei Ohgaki; Yasuo Sakamoto; Shuhei Ito; Akinori Egashira; Hiroshi Saeki; Yoshihiro Kakeji; Masaru Morita; Yoshihisa Sakaguchi; Takeshi Okamura; Yoshihiko Maehara
Journal:  Int J Clin Oncol       Date:  2010-03-12       Impact factor: 3.402

5.  Allelic Losses from Chromosome 17 in Human Osteosarcomas.

Authors:  Marianna Sztán; Zsuzsa Pápai; Miklós Szendrôi; Marco van der Looij; Edith Oláh
Journal:  Pathol Oncol Res       Date:  1997       Impact factor: 3.201

6.  Isolation of differentially expressed genes in carcinoma of the esophagus.

Authors:  M W Graber; C W Schweinfest; C E Reed; T S Papas; P L Baron
Journal:  Ann Surg Oncol       Date:  1996-03       Impact factor: 5.344

Review 7.  Primary adenocarcinomas of lower esophagus, esophagogastric junction and gastric cardia: in special reference to China.

Authors:  Li-Dong Wang; Shu Zheng; Zuo-Yu Zheng; Alan G Casson
Journal:  World J Gastroenterol       Date:  2003-06       Impact factor: 5.742

8.  Genetic features of metachronous esophageal cancer developed in Hodgkin's lymphoma or breast cancer long-term survivors: an exploratory study.

Authors:  Elisa Boldrin; Enrica Rumiato; Matteo Fassan; Rocco Cappellesso; Massimo Rugge; Vanna Chiarion-Sileni; Alberto Ruol; Rita Alfieri; Matteo Cagol; Carlo Castoro; Alberto Amadori; Daniela Saggioro
Journal:  PLoS One       Date:  2015-01-22       Impact factor: 3.240

9.  Qualitative analysis of Adenomatous Polyposis Coli promoter: hypermethylation, engagement and effects on survival of patients with esophageal cancer in a high risk region of the world, a potential molecular marker.

Authors:  Maryam Zare; Ferdous Rastgar Jazii; Mohammad Reza Alivand; Negin Karimi Nasseri; Reza Malekzadeh; Mansour Yazdanbod
Journal:  BMC Cancer       Date:  2009-01-17       Impact factor: 4.430

10.  Frequent loss of heterozygosity on chromosome 17 at 17q11.2-q12 in Barrett's adenocarcinoma.

Authors:  A Swift; J M Risk; A N Kingsnorth; T A Wright; M Myskow; J K Field
Journal:  Br J Cancer       Date:  1995-05       Impact factor: 7.640
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