Literature DB >> 7906533

Influence of carbamazepine on the dose-response relationship of vecuronium.

D G Whalley1, Z Ebrahim.   

Abstract

We have determined the cumulative dose-response relationship for vecuronium from the evoked compound electromyogram of the hypothenar muscles in eight patients who were receiving carbamazepine. The ED50, ED90 and ED95 were 29, 52 and 64 micrograms kg-1, respectively, and were significantly different (P < 0.05) from those of a control group (ED50, ED90 and ED95 21, 36 and 44 micrograms kg-1, respectively).

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Year:  1994        PMID: 7906533     DOI: 10.1093/bja/72.1.125

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  2 in total

Review 1.  Antiepileptic-induced resistance to neuromuscular blockers: mechanisms and clinical significance.

Authors:  Sulpicio G Soriano; J A Jeevendra Martyn
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

Review 2.  Interactions between psychotropics, anaesthetics and electroconvulsive therapy: implications for drug choice and patient management.

Authors:  Mohamed Naguib; Robert Koorn
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

  2 in total

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