Literature DB >> 7906056

Cysteine string proteins: a potential link between synaptic vesicles and presynaptic Ca2+ channels.

A Mastrogiacomo1, S M Parsons, G A Zampighi, D J Jenden, J A Umbach, C B Gundersen.   

Abstract

Presynaptic calcium channels are key regulators of neurotransmitter release. Oocyte expression studies suggest that cysteine string proteins are essential subunits or modulators of these channels. Subcellular fractionation revealed that cysteine string proteins copurify with synaptic vesicles. An average vesicle had eight protein monomers with both the amino and carboxyl termini detected on the cytoplasmic face. Thus, docked synaptic vesicles may regulate presynaptic calcium channels and neurotransmitter release.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7906056     DOI： 10.1126/science.7906056

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  45 in total

1.  Syntaxin modulation of calcium channels in cortical synaptosomes as revealed by botulinum toxin C1.

Authors:  J B Bergsman; R W Tsien
Journal:  J Neurosci       Date:  2000-06-15       Impact factor: 6.167

2.  Enhancement of presynaptic calcium current by cysteine string protein.

Authors:  Shan Chen; Xu Zheng; Karen L Schulze; Terry Morris; Hugo Bellen; Elis F Stanley
Journal:  J Physiol       Date:  2002-01-15       Impact factor: 5.182

3.  Neuroprotection at Drosophila synapses conferred by prior heat shock.

Authors:  S Karunanithi; J W Barclay; R M Robertson; I R Brown; H L Atwood
Journal:  J Neurosci       Date:  1999-06-01       Impact factor: 6.167

4.  Cysteine-string protein increases the calcium sensitivity of neurotransmitter exocytosis in Drosophila.

Authors:  K Dawson-Scully; P Bronk; H L Atwood; K E Zinsmaier
Journal:  J Neurosci       Date:  2000-08-15       Impact factor: 6.167

5.  Dual role of the cysteine-string domain in membrane binding and palmitoylation-dependent sorting of the molecular chaperone cysteine-string protein.

Authors:  Jennifer Greaves; Luke H Chamberlain
Journal:  Mol Biol Cell       Date:  2006-08-30       Impact factor: 4.138

Review 6.  Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets.

Authors:  Ying C Li; Ege T Kavalali
Journal:  Pharmacol Rev       Date:  2017-04       Impact factor: 25.468

7.  rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases.

Authors:  J Debnath; M Chamorro; M J Czar; E M Schaeffer; M J Lenardo; H E Varmus; P L Schwartzberg
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

8.  Traffic of dynamin within individual Drosophila synaptic boutons relative to compartment-specific markers.

Authors:  P S Estes; J Roos; A van der Bliek; R B Kelly; K S Krishnan; M Ramaswami
Journal:  J Neurosci       Date:  1996-09-01       Impact factor: 6.167

9.  Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.

Authors:  H Brown; O Larsson; R Bränström; S N Yang; B Leibiger; I Leibiger; G Fried; T Moede; J T Deeney; G R Brown; G Jacobsson; C J Rhodes; J E Braun; R H Scheller; B E Corkey; P O Berggren; B Meister
Journal:  EMBO J       Date:  1998-09-01       Impact factor: 11.598

10.  Colocalization of calcium entry and exocytotic release sites in adrenal chromaffin cells.

Authors:  I M Robinson; J M Finnegan; J R Monck; R M Wightman; J M Fernandez
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.