Literature DB >> 7903936

Dopamine blocks T-type calcium channels in cultured rat adrenal glomerulosa cells.

O N Osipenko1, P Várnai, A Mike, A Spät, E S Vizi.   

Abstract

Dopamine is known to inhibit aldosterone secretion. In the present study using whole-cell voltage-clamp technique we found that dopamine, bromocriptine and quinpirole inhibit low-threshold (T-type) voltage dependent Ca2+ channels. The inhibiton was sustained and reversible, and it was prevented by sulpiride. These findings indicate that the effect of dopamine was mediated via DA2 receptors.

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Year:  1994        PMID: 7903936     DOI: 10.1210/endo.134.1.7903936

Source DB:  PubMed          Journal:  Endocrinology        ISSN: 0013-7227            Impact factor:   4.736


  4 in total

1.  Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C).

Authors:  Joshua T Wolfe; Hongge Wang; Edward Perez-Reyes; Paula Q Barrett
Journal:  J Physiol       Date:  2002-01-15       Impact factor: 5.182

2.  Two distinct receptors operate the cAMP cascade to up-regulate L-type Ca channels.

Authors:  E A Lukyanetz; P G Kostyuk
Journal:  Pflugers Arch       Date:  1996-06       Impact factor: 3.657

3.  Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers.

Authors:  Changlong Hu; Seth D Depuy; Junlan Yao; William E McIntire; Paula Q Barrett
Journal:  J Biol Chem       Date:  2009-01-08       Impact factor: 5.157

Review 4.  T-Type Calcium Channel: A Privileged Gate for Calcium Entry and Control of Adrenal Steroidogenesis.

Authors:  Michel F Rossier
Journal:  Front Endocrinol (Lausanne)       Date:  2016-05-20       Impact factor: 5.555

  4 in total

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